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  • Who we are
  • What we do
  • Why BioExcellence
  • Our Staffs
  • Worldwide partners
  • Welome to Bio Excellence® international Tech Co.,Ltd.The leading total solution supplier in the life science community.
    Bio Excellence® is a technology leader in providing system solutions for Biosciences,nvironmental and medical research.
    Our expert team of scientists, engineers, and sales professionals have been working in China since 2001. Working closely with the commercial and government scientific communities during the past more than ten years has positioned Bio Excellence® at the forefront of high-tech medical industry.
    Focusing on China, we have earned a deep understanding of the true forces that are behind the rapid modernization in this country. What gives us the edge in China is our priceless and solid network of associates within the private and government research facilities, hospitals, and universities. China is a country that business deals are made through connections and close relationship with the customers. Our mission statement is to support the customer before, during, and after each sale. Once a b and trusted business relationship is established with the customers, they will always remain loyal.

  • Bio Excellence® international Tech Co.,Ltd.is committed to promoting a quality norm for the biotechnology industry in China(include:China Mainland,Hong Kong,Macao,Taiwan). which have been focusing on distributing around the world scientific instruments in China for more than ten years.Bio Excellence® have been looking for foreign manufacturers of scientific equipments for the Chinese researchers, meanwhile open and develop the Chinese market free for you. We are the golden key to open the Chinese market for you.
    We surpass other dealers in the field through our expertise, in part due to our management's b research background and thorough understanding of our customers' needs. We offer timely service and distribute the highest quality goods available in the market. Healthy growth and reputation are the ideas we strive for. In order to achieve these goals, we offer our customers the followings:
    Frequent Information Updates(Need to communicate with customers face to face)
    Timely Delivery
    Swift Service Response
    Sufficient Pre or Post-sale Technical Support
    With the objective of providing the highest quality Pre & Post-sale services to our customers, we regularly send our in-house application scientists and maintenance engineers for overseas trainings arranged by the suppliers. This training is necessary in making sure that we have sufficient technical knowledge to comprehensively answer customers' problems and inquiries efficiently.
    Being a regional distributor to our suppliers, we have undertaken the responsibility of providing an efficient procurement-distribution-fulfillment solution and to arrange promotional activities, such as exhibitions, seminars, workshops, and road shows. Bio Excellence® also maintains very close relationships with the suppliers to provide post-sales services to customers, including technical and application support.
    Apart from distribution, We also engaged in providing medical research consulting and technical services for clinical doctors. Its services include research project design & implementation, data processing & analysis, and research reports summarization.

  • We have employed a professional team led by full-time scientists who used to work in the world-renowned institutions. Our technical team is especially expert in eight areas of research, including medical cell biology, animal disease models, medical molecular biology, medical electrophysiology, medical nano material, medical genetics and bioinformatics, pathology and medical imaging, drug research and development.

  • BIO EXCELLENCE® INTERNATIONAL Tech Co.,Ltd, we have successfully acquired exclusive distributorships in China(include:China Mainland,Hong Kong,Macao,Taiwan) from a number of world-class manufacturers, such as:
    Flexcellint
    Tissue Growth
    OPtics11
    cellscale
    cellixltd
    SKE
    Aurorascientific
    regenHU
    Celltool
    SymCel
    Cellsorter
    nanotherics
    lazarlab
    orflo
    cytoo
    synvivobio
    orflo
    picotwist
    Biospace
    lumicks
    Embitec

  • Mechanobiology
  • Micromanipulator
  • 3D Printer
  • Cellsorter&Analyzer
  • 1.Optical Stretcher

    Features:
    single cell analysis with laser beams,a novel laser tool to measure and analyse biomechanical properties!The optical stretcher is a novel laser tool to micromanipulate single biological cells and to probe their viscoelastic properties in suspension.Based microfluidic technology for high-throughput analysis of single cell traction and measurement;Automated measurement and imaging properties of single cell force recorded cell deformation record
    1)Contact-free cell deformation
    Contact-free cell deformation” open=”0″ style=”2″]Suspended cells are deformed by optical forces, leading to absolutely contact-free measurements. This ensures homogeneous cell handling and avoids artefacts due to contact-induced cellular reactions.
    2)Timesaving, automated measurements
    Cells are automatically delivered to the measurement region and deformed corresponding to the user-defined stretch pattern. While the Optical Stretcher runs the experiment you can focus on interpreting results.
    3)High-throughput single cell rheology
    By integration of a microfluidic system about 300 cells/hour can be measured with ease. This allows for the first time to collect significant statistical data from cell rheology.
    4)Better statistics compared to AFM
    A cell is trapped by two opposing laser beams, which hold it and pull on both sides of it. Higher laser powers are used to deform the cell. The cell deformations are recorded by a CCD camera and evaluated by a custom designed software. The measurement chamber of the Optical Stretcher is integrated into a microfluidic system, such that cells can be easily delivered one after the other. High throughput rates of about 250 cells per hour can be achieved, allowing for better statistics compared to other tools such as atomic force microscopy (AFM).

    2.Single Molecule Biophysics Magnetic Trap—Stretching and twisting single molecules

    Features:
    PicoTwist is involved in nanomanipulation and single-molecule experiments in biology. Historically, single molecule experiments were among the first nanotechnologies, appearing in the 1990s to characterize biopolymers and proteins with unprecedented accuracy. The idea is that instead of analyzing the behavior of a great number of molecules as usually done in a test tube, you now analyze the behavior of a single molecule. Thus instead of measuring average behavior you have direct access to the biopolymer’s activity in real time.

    3.Chiaro Nanoindenter

    Features:
    Compatible with microscopes
    The Chiaro Nanoindenter is designed to be compatible with almost any inverted microscope to enable the simultaneous practice of advanced microscopy and micro-mechanical characterization.
    Features Chiaro Nanoindenter
    The Chiaro Nanoindenter is engineered with flexibility in mind. Due to the almost limitless mounting options and low footprint of our nanoindentation probes, the Chiaro can be combined with many microscopes or other optical set-ups, even simultaneous with other instruments such as electrophysiology equipment, patch clamping instruments, perfusion or heating stage chambers, and many more!
    Standard versus dynamic
    The standard version of the Piuma and Chiaro Nanoindenter includes all the tools required for performing displacement-controlled experiments, including automatically mapping the micro-mechanical properties of surfaces. The Piuma and Chiaro Nanoindenter are available with a dynamic module, expanding the modes of operation with load-, indentation-, and frequency control.

    4.Piuma Nanoindenter

    The Piuma Nanoindenter is designed to operate as a stand-alone instrument in any lab setting. Amongst many applications possible, the Piuma can be used to perform comparative studies on biological samples such as cartilage, dermis or cornea, optimize and select between polymer or hydrogel synthesis or crosslinking procedures or define material performance parameters such as surface adhesion, swelling or degradation, also in liquids.
    Features:
    Easy operation due to the built-in camera (top-view, 5X) and the coarse manual Z-stage. Almost any sample size or shape can be used thanks to the large sample stage. Optionally a sample stage heater is available (from room temperature up to 60oC), a back light illumination module, an inverted camera module for small or transparent samples and an acrylic housing for use in more noisy environments.

  • RegenHU 3Ddiscovery 3D bio-printing platform

    The 3DDiscovery® instrument is a cost-effective 3D bio-printing platform to explore the potential of 3D tissue engineering through the bio-printing approach.

    RegenHU BioFactory® high end, versatile and cell friendly three dimensional bio-manufacturing instrument

    The BioFactory® is a high end, versatile and cell friendly three dimensional bio-manufacturing instrument. It allows researchers to pattern cells, biomolecules and a range of soft and rigid materials in desirable 3D composite structures in order to mimic biomimetic tissue models.

  • Neuroindx UnipicK vacuum-assisted single cell collection and tissue microdissection

    UnipicK is a vacuum-assisted single cell collection and tissue microdissection instrument based on NeuroInDx’s original capillary-based cell and tissue acquisition system (CTAS; USPT 8,797,644; Kudo et al, 2012) that can acquire individual cells from cell cultures and tissues. It permits rapid acquisition of single cells from any untreated cell cultures, providing reliable and affordable means of most sophisticated experimentation. Moreover, the instrument is suitable for individual cell collection and region specific acquisition of subanatomical areas from complex heterogeneous tissues such as the brain. Operation of the system is intuitive and requires minimal training. Cell cultures require no treatment or specific peripherals, thus enabling unmatched flexibility in experimental design and sample collection.
    Perhaps one of the most distinct features is the ability of UnipicK™ to collect live cells for further reculturing and a plethora of downstream functional studies. Both individual fluorescently labeled and morphologically distinct cells can be acquired from any cell cultures or tissue sections. The procedure has been demonstrated from nearly all types of adherent, suspended and 3D cultures, including difficult samples such as primary cells, or individual cells from fresh frozen and sucrose treated complex tissues, such as brain (please, see http://www.youtube.com/user/NDXInc). With live cells viability tests have demonstrated up to 99% after collection, and up to 30 cells per minute may be collected from adherent cultures.
    Notable Features of UnipicK™ include:
    – Simple operation with minimal training
    – Single cell collection from untreated cultures and tissue sections
    – Efficient tissue microdissection
    – High viability of collected cells
    – High quality RNA and protein for downstream – omics studies
    – Flexibility and versatility – fit any inverted microscope
    – Fraction of the cost of any laser assisted microdissection instrument

    UnipicK+ tissue microdissection, single cell acquisition, and deposition platform

    UnipicK+ is a universal platform for tissue microdissection, single cell acquisition, and deposition into the single wells for further molecular analysis or clonal expansion. The main working principle is based on the capillary based vacuum pulse assisted technology (CTAS; Kudo et al, 2012). Developed system can microdissect tissue sections, collect and deposit individual cells from any adherent cultures grown in standard cell culture dishes in as small as 15 nl volume, compatible with various downstream single cell analyses and next generation sequencing. Like UnipicK, the system may be used with a wide range of inverted microscopes. The benefits include cost-efficiency, simple operation, digital interface, complete workflow from single cell isolation to downstream analysis, compatibility with a wide range of inverted microscopes and use of standard plates and culture dishes.

    CellSorter High throughput single cell sorting

    High throughput single cell sorting directly from the Petri dish
    One single cell arrives to each PCR tube
    10 PCR strips containing 80 tubes can be filled in a cycle
    Glass cover slip for testing single cell deposition in situ
    Drop volume less than 1 ul for adherent cells
    Pick up volume of ~1 nl for suspended cells
    15-20 seconds per cell. When collecting multiple cells, sorting speed is 1 cell/second.
    Number of cells picked up in a single run: 1-1000.
    Isolates a subpopulation of live adherent cells expressing fluorescent or luminescent markers
    Both unlabeled and fluorescentcells are recognized by computer vision
    Viable cells after sorting
    Any adherent and non-adherent cell type can be sorted
    Cell culture needs minimal preparation before sorting
    Average sorting process takes only a few minutes
    Multichannel detection using the fluorescent filter setup of the microscope

  • Imaging analysis
  • Sports
    biomechanics
  • Single-Use-
    Bioreactor
  • Turnkey TIRF Microscopy complex

    Turnkey TIRF Microscopy complex is compatible with Nikon, Olympus, Zeiss, and Leica
    1)inverted microscopes. The complex includes:
    2)Prism-based p-TIRFM flow system, and/or
    3)Lightguide-based lg-TIRFM flow system, and/or
    4)Objective-based o-TIRFM flow system
    5)Multi-color computer-controlled illuminator
    6)Low light EMCCD camera Andor iXon or similar
    7)Optional digital fluidics SmartFlow
    8)Optional temperature control system TC-40 – 25-40oC
    9)Optional filter-wheel EW-6 at emission channel
    10)Optional electrochemical control unit EC-1070
    TIRF Labs supplies turnkey TIRFM complex with TIRF Studio software package, which controls
    MCI-7000 illuminator, Andor EMCCD cameras, digital fluidics SmartFlow, temperature control
    TC-40, filter-wheel EW-6, and electrochemical unit EC-1070. Microscope is not included. TIRF
    Labs will collaborate with microscope supplier of your choice to provide seamless integration of
    TIRFM complex with the microscope.
    applications:
    Cell biology studies
    Molecular diagnostics
    Analysis of biomolecular interactions
    Monitoring real-time kinetics of biomolecular interactions
    Real-time TIRF microarrays
    Combined DNA, RNA, protein, and metabolite arrays
    Studies of protein-protein and protein-DNA interactions
    Studies of surface supported membranes
    Lipid rafts studies
    Nanoengineering
    Drug screening
    Lead optimization
    Bioassay development, and more ..

  • Optoelectronic Plethysmography System for the analysis of breathing mechanics

    OEP System measures the volume of the chest wall and its variation during breathing, using reflective and non invasive markers attached to the thoraco-abdominal skin by biadhesive hypoallergenic tape. The three-dimensional positions of the markers are obtained thanks to infrared light video cameras with flashing LED’s.
    OEP System, with the use of advanced algorithms, also measures the different compartments of the chest wall, provides the continuous monitoring of all ventilatory parameters (tidal volume, frequency inspiratory and expiratory times, etc.) and allows to track end-expiratory and end-inspiratory lung volume variations on a breath-by-breath basis.
    OEP System does not require the use of a mouthpiece or any other physical connection to the patient. Patient’s active participation is not required, making it suitable for the use in Intensive Care Units, when the patient is under anesthesia, during sleep, or when the patient is an infant. It is also suitable for prolonged measurements and the calibration of the system is not subject-specific and does not require the execution of any maneuver by the subject.
    OEP System can be combined with any other measurement, such as flow, pressures, gases concentration, EMG, ultrasonography, haemodynamics, sound, etc. For instance, the combination with esophageal and gastric pressure makes it possible to study the dynamics and energetics of respiratory muscles. It can be carried out in different positions (sitting, standing, supine, prone) and applied during situations like rest, exercise, sleep, mechanical ventilation, functional electrical stimulation, phonation, singing and forced oscillation.
    Characteristics
    easy to use and non-invasive for the patient (intensive care, sleep, children...);
    suitable for a prolonged measurement (it doesn’t suffer of drift problems);
    can be performed in any posture (sitting, supine,..) and under any experimental condition (rest, exercise, phonation,..);
    does not require any connection with the patient, like a mouthpiece or a facial mask that could reduce the subject mobility, alter the natural pattern of breathing or introduce additional dead space;
    volume measurement is not influenced by ambient factor (temperature, humidity and gas composition);
    does not require a specific calibration for each patient;
    provides an accurate measurement of the different compartments of the chest wall (pulmonary rib cage, abdominal rib cage, abdomen, eventually split into their right and left parts).

    Real-time 3D motion capture system

    The MotionMonitor®
    The MotionMonitor is a turnkey 3D motion capture system with software for biomechanics research and rehabilitation. It is designed to synchronously collect data from optical trackers, inertial measurement units, EMG sensors, force plates, hand transducers, EEG systems, digital video, event markers and other analog devices, virtual reality, and haptic devices. Data generated from a rich collection of analytical tools are immediately available for playback with graphical displays of all data outputs and stunning 3D computer graphics and subject animations. Real-time measurement and kinematic analysis of the human body's movement, brain activity, eye movement, muscle recruitment, and external forces acting on the body is achieved using the broadest range of hardware available in the market.

  • Superior Mixing and Mass transfer SINGLE-USE BIOREACTOR

    Feature:
    Single-Use Bior eactor for both Micr obial Fermentation and Mammalian cultures.
    Superior Mixing and Mass transfer.
    Cell culture and Microbial Fermentation.
    System supports both microbial fermentation and mammalian cultures.
    Easy process development and seed-train set-up.
    Full measurement and control, including cooling.

    Superior Mixing and Mass transfer SINGLE-USE BIOREACTOR

    Feature:
    Easy to buy, install and use – provides simplicity, less labour intensive and enables fast set up times.
    Simple set up procedure and systems programming – allows cultures to be set up with minimal hands-on time (<30mins)
    Single-use culture bags – eliminates cleaning requirements, cross contamination and minimises down-time.
    Provides highly accurate control conditions including temperature control (15&dreg;C – 45&dreg;C) with built-in chiller – no external chilling/heating equipment needed and gives optimal production of higher ODs of soluble protein.
    Oxygen generation capability (up to 4 litres / minute) – eliminates need, and extra cost, of oxygen gas supply.
    Higher efficiency of oxygen transfer – potential of protein production at higher ODs.
    Efficient airlift technology – delivers very efficient, controllable aeration and mixing, with minimal sheering and eliminating cell settling.
    Higher performance than shaker flasks and comparable performance to steel/glass stirred systems – optimal protein yields with ease of use.
    Connects to bioreactor cell culture bags via autoclavable, reusable sterile filters – minimises running costs.
    Programmable air/enriched air flow rate (1-10 litres per minute) – provides very efficient mixing and aeration to improve protein yields.

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