加拿大cellscale生物组织材料机械力特性测试分析仪

型号:内详
价格:请致电:010-67529703
品牌:cellscale

CellScale的生物反应器为细胞和组织及其它材料对机械刺激的反应提供了深入的洞察。cellscale系统针对高通量、实时成像、3D支架使用和多模式刺激进行了优化。CellScale在开发定制解决方案方面拥有丰富的经验,效果屡超客户预期。

机械测试系统。

在CellScale,我们的测试系统从头到尾进行了优化,以表征生物材料的力学性能。环境舱和成像实现了完整的系统功能,省去了后顾之忧。 能满足从微尺度压缩到双轴拉伸的需求,CellScale的系统能提供值得信赖的尖端数据。



一、BioTester双轴材料

专为生物材料而打造的一套设备齐全的双轴测试系统

由于其定向取向的微观结构,双轴测试对于理解生物材料的机械性能而言是至关重要的。BioTester系统的设计使双轴测试变得简单,使用户可以专注于结果而不是测试本身。

主要优势

  • 4个高性能的执行机构,带有直列加载传感器
  • 使用基于图像应变测量工具的高分辨率CCD成像
  • 包括专利BioRakes在内的多种附着选项,可快速可靠地安装样品
  • 集成温控介质浴
  • 功能齐全的用户界面软件,可进行实时反馈的简单、循环、松弛和多模式测试


试样和安装

BioRake样品安装系统使用了CellScale专利技术的附着软组织和生物材料的方法。

每根尖齿都经过电化学锐化,可以轻松刺穿最硬和最脆弱的组织样本。每套都永久性地连接到一个共同的基座,可以同时刺穿所有20个连接点。磁力安装的BioRakes便于清洁或更换,可以实现BioRake、平衡滑轮和夹具安装系统之间的轻松转换。

进行测试时,使用手动升降机构将样本定位并升高到位,并施加压力以将钩子插入组织中。样品因此可以在几秒钟内安装好并做好分析准备。安装一气呵成、准确易操作。

BioRakes的齿间距从0.7毫米到2.2毫米不等,以适应从3到15毫米大小的标本。

BioRake样品安装系统

平衡滑轮样品安装系统提供了CellScale在双轴测试过程中确保零剪切应力的附着方法

两个双端定制缝合钩被用来在样品的每一侧上创建4个附着点。两级不锈钢滑轮机构确保在测试过程中每根缝线保持相同的张力。

滑轮机构采用磁性安装方式,便于拆卸清洁,并使BioRake、平衡滑轮和夹具安装系统之间轻松过渡。

平衡滑轮安装系统

夹具样品安装系统提供了CellScale失败测试的附着方法。

使用十字形试样可以让比基础材料更弱的附着位置远离试样的测量区域移动。夹具让样品可以很容易地加载并且牢固地就位。

不锈钢夹紧机构安装在与其他附着系统相同的支架上,以便在BioRake、平衡滑轮和夹具安装系统之间快速简单的转换。

还可以进行定制夹具设计,以适应您的组织对夹紧力和夹紧表面的要求。

夹具安装系统


软件

BioTester的设置、操作和数据收集软件模块让标准或定制测试规程的执行变得容易。

测试参数(如位移量、持续时间和数据/图像采集速率)以表格格式指定,以便快速访问和修改。位移和受力测试都可以针对每个轴独立指定。一旦建立了协议,就可以使用模板系统快速重新加载所需的测试参数。

软件界面在测试设置期间向用户提供实时成像和当前的力、位置和温度的信息。在测试运行时,软件提供实时结果图形和实时视频馈送,以方便用户监视测试进度。

如果询问使用我们设备的用户,他们会很快告诉您这个软件包是多么的直观和有用。

 

BioRake样品安装系统


双轴测试的很大一部分是理解和解释收集到的数据。

BioTester包含一个图像分析软件模块,可用于查看和分析测试图像,提供有价值的定量和定性信息。该模块可以用来导出用于演示目的.avi视频或带有数据叠加层的图像。

BioTester包含一个高分辨率的相机,在测试过程中可以很好地观察样品。所收集的图像(按用户指定的频率)自动和力位移数据进行时间关联,以便软件模块可以将所有的测试信息供用户选用。

软件模块的图像跟踪功能可以快速轻松地分析测试图像,以确定样本表面上一个或多个点的平面内运动。这个跟踪信息提供了直接的标本应变测量,而不依靠由夹点运动计算的应变。通过追踪多点组成的网格,可以研究样品不同区域的应变。


平衡滑轮安装系统


二、UniVert单轴拉伸、压缩和扭力测试分析

随时随地进行您需要的机械测试

UniVert是各种机械测试应用的理想选择,它的占地面积小,价格合理,使用户可以随时随地进行测试。易于使用的软件和可互换的组件使得系统无需大量的培训或督导即可使用。

该系统能够承受高达200N的拉伸、压缩和弯曲测试。各种夹具和固定装置可用于适应不同的标本和测试模式。

主要优势

  • 小体量即可进行质量好、性价比高的测试
  • 夹具和加载传感器的变化易于操作,可以适应各种用途。
  • 使用基于图像的应变测量工具,可实现高分辨率CCD成像(可选)
  • 功能齐全的用户界面软件,可通过实时反馈进行简单、循环、松弛和多模式测试
参数:
外形尺寸 22 X 22 X 54cm
重量 8kg
力的大小 200N
可用的加载传感器 10, 20, 50, 100, 200N
力的准确性 加载传感器容量的0.2%
最大夹点分离 140mm
最大速度 20mm/s
最大循环频率 2Hz
最大数据速率 100Hz

三、MicroSquisher压缩、拉伸、弯曲、压痕和剪切测试

MicroSquisher是一个微型机械测试系统,可以做别人所不能做之事。更小的标本,更好的解像力,更容易的测试设置和极佳的视觉效果。应用包括小组织样品,水凝胶微球,细胞球体和工程化组织生长基质。

主要优势

  • 压缩、拉伸、弯曲、压痕和剪切测试的测试模式
  • 0.1μm分辨率的高精度压电执行器
  • 解像力降至10nN
  • 高分辨率的CCD成像
  • 集成温控介质浴
  • 功能齐全的用户界面软件,可进行实时反馈的简单、循环、松弛和多模式测试

试样和安装

平行板压缩
样品:300μm水凝胶微球(30KPa)
峰力:20mN

悬臂弯
试样:20μm厚、4mm宽箔带(70MPa)
峰力:3mN

平行板压缩
标本:直径2毫米的水凝胶圆柱体(12KPa)
峰力:20mN

球形压痕
样品:1.5mm直径压头压入水凝胶(2KPa)
峰力: 12mN

弯曲引起的拉伸
标本:蜘蛛丝
峰力:2mN

穿刺附着拉伸
样品:3.5mm宽,1.5mm厚的水凝胶(0.5KPa)
峰力:1.4mN

四、UStretch用于生物材料的多功能单轴台式机械测试仪


UStretch不仅限于大型试样夹点的干燥垂直测试。它还可以在温控或非温控的介质槽内进行垂直和水平测试。 他们的系统还有各种各样的样品附件,包括螺杆驱动夹具、弹簧夹具和多点刺穿夹具。

主要优势

  • 带有直列式加载传感器的高性能执行器
  • 使用基于图像的应变测量工具,拥有高分辨率CCD成像
  • 有包括专利产品BioRakes在内的多种附件选件,可快速可靠地安装样品
  • 集成温控介质浴
  • 功能齐全的用户界面软件,可通过实时反馈进行简单、循环、松弛和多模式测试

试样和安装

BioRake

获得专利的BioRake附着系统可以使标本快速准确地安装。

BioRake样品安装系统

机械夹点

机械夹点附着系统有利于实现更大的力量和进行样本失败测试。

机械夹点

软件

集成的软件可以轻松指定简单或复杂的测试规程。测试规程可以保存和修改。实时的力量和位移图形有助于测试验证。

UStretch软件与BioTester 软件构建在同一个平台上。 .

Ustretch 软件

成像系统

可选的成像系统和分析软件可以对图像进行分析,以验证样品的应变和应变的均匀性。

Ustretch 软件

应用文献:


Instrument

Year

Title

Author

Link

BioTester

2018

Biaxial mechanical behavior of bovine saphenous venous valve leaflets

J. Lu, H-Y S. Huang

View Article

UniVert

2018

Mechanical Strength Of Nafion®/ZrO2 Nano-Composite Membrane

R. Sigwadi, F. Nemavhola, S. Dhlamini, T. Mokrani

View Article

MechanoCulture B1

2018

Role of boundary conditions in determining cell alignment in response to stretch

K. Chen, A. Vigliotti, M. Bacca, R. M. McMeeking, V.S. Dashpande, J.W. Holmes

View Article

BioTester

2018

Prevalence of Calcification in Human Femoropopliteal Arteries and its Association with Demographics, Risk Factors, and Arterial Stiffness

A. Kamenskiy, W. Poulson, S. Sim, A. Reilly, J. Luo, J. MacTaggart

View Article

BioTester

2018

Comparison of corneal biomechanics after myopic small-incision lenticule extraction compared to LASIK: an ex vivo study

A.J. Kanellopoulos

View Article

UniVert

2018

Three-Dimensional Printing of Bisphenol A-Free Polycarbonates

W. Zhu, S-H. Pyo, S. You, C. Yu, J. Alido, J. Liu, Y. Leong, S. Chen

View Article

BioTester

2018

Dehiscence of patch augmentation of a left-sided atrioventricular valve related to strenuous isometric exercise: Case report and failure analysis

P.E. Hammer, C.W. Baird, P.J. del Nido, G.R. Marx

View Article

BioTester

2018

Puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization

A.A. Ksiazek, L. Frese, P.E. Dijkman, B. Sanders, S. E. Motta, B. Weber, S.P. Hoerstrup

View Article

BioTester

2018

Biomechanical evaluation of a personalized external aortic root support applied in the Ross procedure

J. Vastmans, H. Fehervary, P. Verbrugghe, T. Verbelen, E. Vanderveken, J. Vander Sloten, T. Treasure, F. Rega, N. Famaey

View Article

BioTester

2018

Polydopamine as sizing on carbon fiber surfaces for enhancement of epoxy laminated composites

W. Han, H-P. Zhang, J. Tavakoli, J. Campbell, Y. Tang

View Article

BioTester

2018

Comparison of in vivo vs. ex situ obtained material properties of sheep common carotid artery

M. Smoljkic, P. Verbrugghe, M. Larsson, E. Widman, H. Fehervary, J. D'hooge, J. Vander Sloten, N. Famaey

View Article

BioTester

2018

Soy Protein/Cellulose Nanofiber Scaffolds Mimicking Skin Extracellular Matrix for Enhanced Wound Healing

S. Ahn, C.O. Chantre, A.R. Gannon, J.U. Lind, P.H. Campbell, T. Grevesse, B.B. O'Conner, K.K. Parker

View Article

BioTester

2018

New findings confirm the viscoelastic behaviour of the inter-lamellar matrix of the disc annulus fibrosus in radial and circumferential directions of loading

J. Tavakoli, J.J. Costi

View Article

Ustretch

2018

Self-assembled Collagen-Fibrin Hydrogel Reinforces Tissue Engineered Adventitia Vessels Seeded with Human Fibroblasts

B. Patel, Z. Xu, C. Pinnock, L.S. Kabbani, M.T. Lam

View Article

BioTester

2018

3D printed, controlled release, tritherapeutic tablet matrix for advanced anti-HIV-1 drug delivery

M. Siyawamwaya, L.C. du Toit, P. Kumar, Y.E. Choonara, P.P.P.D Kondiah, V. Pillay

View Article

MicroSquisher

2018

Acrylate-based materials for heart valve scaffold engineering

R. Santoro, S. Venkateswaran, F. Amandeo, R. Zhang, M. Brioschi, A. Callanan, M. Agrifoglio, C. Banfi, M. Bradley, M. Pesce

View Article

BioTester

2018

Computational modeling guides tissue-engineered heart valve design for long-term in vivo performance in a translational sheep model

M.Y. Emmert, B.A. Schmitt, S. Loerakker, B. Sanders, H. Spriestersbach,, E.S. Fioretta, L. Bruder, K. Brakmann, S.E. Motta, V. Lintas, P.E. Dijkman, L. Frese, F. Berger, F.P.T. Baaijens, S.P. Hoerstrup

View Article

UniVert

2018

Fabrication of functionalized citrus pectin/silk fibroin scaffolds for skin tissue engineering.

S. Tukkan, D. Atila, A. Akdaq, A. Tezcaner

View Article

UniVert

2018

Rapid continuous 3D printing of customizable peripheral nerve guidance conduits

W. Zhu, K.R. Tringale, S.A. Woller, S. You, S. Johnson, H. Shen, J. Schimelman, M. Whitney, J. Steinauer, W. Xu, T.L. Yaksh, Q.T. Nguyen, S.Chen

View Article

MicroSquisher

2018

A Microvascularized Tumor-mimetic Platform for Assessing Anti-cancer Drug Efficacy

S. Pradhan, A.M. Smith, C.J. Garson, I. Hassani, W.J. Seeto, K. Pant, R.D. Arnold, B. Prabhakarpandian, E.A. Lipke

View Article

UniVert

2017

A highly deformable conducting traces for printed antennas and interconnects: silver/fluoropolymer composite amalgamated by triethanolamine

A. Kumar, H. Saghlatoon, T-G. La, M. M. Honari, H. Charaya, H.A. Damis, R. Mirzavand, P. Mousavi, H-J. Chung

View Article

MicroSquisher

2017

A three-dimensional spheroidal cancer model based on PEG-fibrinogen hydrogel microspheres

S.Pradhan, J. M. Clary, D. Seliktar, E. A. Lipke

View Article

BioTester

2017

Biaxial experimental and analytical characterization of a dielectric elastomer

A. Helal, M. Doumit, R. Shaheen

View Article

BioTester

2017

Biaxial mechanical properties of bovine jugular venous valve leaflet tissues

H-Y. S. Huang, J. Lu

View Article

BioTester

2017

Comparison of Femoropopliteal Artery Stents Under Axial and Radial Compression, Axial Tension, Bending, and Torsion Deformations

K. Maleckis, P. Deegan, W. Poulson, C. Sievers, A. Desyatova, J. MacTaggart, A. Kamenskiy

View Article

BioTester

2017

Constitutive modeling of human femoropopliteal artery biaxial stiffening due to aging and diabetes

A. Desyatova, J. MacTaggart, A. Kamenskiy

View Article

BioTester

2017

Constitutive modeling of jugular vein-derived venous valve leaflet tissues

N. Kaul, H-Y. S. Huang

View Article

MicroSquisher

2017

Decellularized adipose tissue microcarriers as a dynamic culture platform for human adipose-derived stem/stromal cell expansion

C. Yu, A. Kornmuller, C. Brown, T. Hoare, L.E. Flynn

View Article

BioTester

2017

Design and characterization of a hyperelastic tubular soft composite

R. Shaheen, M. Doumit, A. Helal

View Article

MicroSquisher

2017

Encapsulation of Equine Endothelial Colony Forming Cells in Highly Uniform, Injectable Hydrogel Microspheres for Local Cell Delivery

W.J. Seeto, Y. Tian, R.L. Winter, F.J. Caldwell, A.A. Wooldridge, E.A. Lipke

View Article

BioTester

2017

In situ heart valve tissue engineering using a bioresorbable elastomeric implant – From material design to 12 months follow-up in sheep

J. Kluin, H. Talacua, A.I.P.M. Smits, M. Y. Emmert, M.C.P. Brugmans, E.S. Fioretta, P.E. Dijkman, S.H.M. Sontjens, R.Duijvelshoff, S. Dekker, M.W.J.T. Janssen-van den Broek, V. Lintas, A. Vink, S.P. Hoerstrup, H.M. Janssen, P.Y.W. Dankers, F.P.T. Baaijens, C.V.C. Bouten

View Article

BioTester

2017

JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement

A.K. Capulli, M.Y. Emmert, F.S. Pasqualini, D. Kehl, E. Caliskan, J.U. Lind, S. P. Sheehy, S.J. Park, S. Ahn, B. Weber, J.A. Goss, S.P Hoerstrup, K.K. Parker

View Article

BioTester

2017

Limb flexion-induced twist and associated intramural stresses in the human femoropopliteal artery

A. Desyatova, W. Poulson, P. Deegan, C. Lomneth, A. Seas, K. Maleckis, J. MacTaggart, A. Kamenskiy

View Article

MechanoCulture T6

2017

Living nanofiber yarn-based woven biotextiles for tendon tissue engineering using cell tri-culture and mechanical stimulation

S. Wu, Y. Wang, P.N. Streubel, B. Duan

View Article

MechanoCulture FX

2017

Mechanical and signaling roles for keratin intermediate filaments in the assembly and morphogenesis of mesendoderm tissue at gastrulation

P.R. Sonavane, C. Wang, B. Dzamba, G.F. Weber, A. Periasamy, D.W. DeSimone

View Article

BioTester

2017

Mechanically Robust Electrospun Hydrogel Scaffolds Crosslinked via Supramolecular Interactions

B.B. Mollet, S. Spaans, P.G. Fard, N.A.M. Bax, C.V.C. Bouten, P.Y.W. Dankers

View Article

MicroSquisher

2017

Microfluidic production of degradable thermoresponsive poly(N-isopropylacrylamide)-based microgels

D. Sivakumaran, E. Mueller, T. Hoare

View Article

BioTester

2017

Nondestructive mechanical characterization of developing biological tissues using inflation testing

P.J.A. Oomen, M.A.J. van Kelle, C.W.J. Oomens, C.V.C. Bouten, S. Loerakker

View Article

BioTester

2017

On the influence of wall calcification and intraluminal thrombus on prediction of abdominal aortic aneurysm rupture

H.E. Barrett, E.M. Cunnane, H. Hidayat, J.M. O'Brien, M.A. Moloney, E.G. Kavanagh, M.T. Walsh

View Article

BioTester

2017

Paraspinal Muscle Passive Stiffness Remodels in Direct Response to Spine Stiffness: A Study Using the ENT1-Deficient Mouse

K. Gsell, D. Zwambag, D.E. Fournier, C.A. Seguin, S.H.M. Brown

View Article

MicroSquisher

2017

PEG-fibrinogen hydrogels for three-dimensional breast cancer cell culture

S. Pradhan, I. Hassani, W.J. Seeto, E.A. Lipke

View Article

MicroSquisher

2017

Polysaccharide Hydrogels Support the Long-Term Viability of Encapsulated Human Mesenchymal Stem Cells and Their Ability to Secrete Immunomodulatory Factors

F. Hached, C. Vinatier, P-G. Pinta, P. Hulin, C. Le Visage, P. Weiss, J. Guicheux, A. Billon-Chabaud, G. Grimandi

View Article

MicroSquisher

2017

Pullulan microbeads/Si-HPMC hydrogel injectable system for the sustained delivery of GDF-5 and TGF-β1: new insight into intervertebral disc regenerative medicine

N. Henry, J. Clouet, A. Fragale, L.Griveau, C. Chedevile, J. Veziers, P. Weiss, J. Le Bideau, J. Guicheaux, C. Le Visage

View Article

MicroSquisher

2017

Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy

D. Gillies, W. Gamal, A. Downes, Y. Reinwald, Y. Yang, A.J. El Haj, P.O. Bagnaninchi

View Article

UniVert

2017

Self-reinforcing graphene coatings on 3D printed elastomers for flexible radio frequency antennas and strain sensors

X. Li, M.M. Honari, Y. Fu, A. Kumar, H. Saghlatoon

View Article

MechanoCulture FX

2017

Tenogenic phenotype maintenance and differentiation using macromolecular crowding and mechanical loading

D. Gaspar, A. Pandit, D. Zeugolis

View Article

BioTester

2017

Tensile behaviour of individual fibre bundles in the human lumbar anulus fibrosus

D.T. Pham, J.G. Shapter, J.J. Costi

View Article

MicroSquisher

2017

The physical basis of coordinated tissue spreading in zebrafish gastrulation

H. Morita, S. Grigolon, M. Bock, S.F.G. Krens, G. Salbreux, C-P. Heisenberg

View Article

MicroSquisher

2017

The role of adhesion junctions in the biomechanical behaviour and osteogenic differentiation of 3D mesenchymal stem cell spheroids

F.E. Griffin, J. Schiavi, T.C. McDevitt, J.P. McGarry, L.M. McNamara

View Article

BioTester

2017

Urinary Bladder Versus Gastrointestinal Tissue: a Comparative Study of Their Biomechanical Properties for Urinary Tract Reconstruction

N.F. Davis, J.J.E. Mulvihill, S. Mulay, E.M. Cunnane, D.M. Bolton, M.T. Walsh

View Article

BioTester

2016

A comparison between porcine, ovine, and bovine intervertebral disc anatomy and single lamella annulus fibrosis tensile properties

L.A. Monaco, S.J. DeWitte-Orr, D.E. Gregory

View Article

BioTester

2016

Acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro

A.K. Capulli, L.A. MacQueen, B.B. O'Conner, S. Dauth, K.K. Parker

View Article

MechanoCulture T6

2016

Additive manufacturing of a photo-cross-linkable polymer via direct meld electrospinning writing for producing high strength structures

F. Chen, G. Hochleitner, T. Woodfield, J. Groll, P. Dalton, B.G. Amsden

View Article

BioTester

2016

Age-Dependent Changes in Geometry, Tissue Composition and Mechanical Properties of Fetal to Adult Cryopreserved Human Heart Valves

D. van Geeman, A.L.F. Soares, P.J.M. Oomen, A. Dressen-Mol, M.W.J.T. Janssen-van den Broek, A.J. van den Bogaerdt, J.J.C. Bogers, M-J. T.H. Goumans, F.P.T. Baaijens, C.V.C. Bouten

View Article

MicroSquisher

2016

An Injectable Hydrogel Prepared Using a PEG/Vitamin E Copolymer Facilitating Aqueous-Driven Gelation

J. Zhang, B. Muirhead, M. Dodd, L. Liu, N. Mangiacotte, T. Hoare, S. Sheardown

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BioTester

2016

Are adipose-derived stem cells cultivated in human platelet lysate suitable for heart valve tissue engineering

L. Frese, T. Sasse, B. Sanders, F.P.T. Baaijens, G.M. Beer, S.P. Hoerstrup

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BioTester

2016

Biaxial quantification of deep layer transverse carpal ligament elastic properties by sex and region

B. Mathers, A. Agur, M. Oliver, K. Gordon

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BioTester

2016

Biomechanical Characterization of Ascending Aortic Aneurysms

M. Smoljkic, H. Fehervary, P. Van den Bergh, A. Jorge-Penas, L. Kluyskens, S. Dymarkowski, P. Verbrugghe, B. Meuris, J. Vander Sloten, N. Famaey

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BioTester

2016

Biomechanical properties and microstructure of heart chambers: a paired comparison study in an ovine model

S. Javani, M. Gordon, A.N. Azadani

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BioTester

2016

Characterization of three-dimensional anisotropic heart valve tissue mechanical properties using inverse finite element analysis

M. Abbasi, M.S. Barakat, K. Vanhidkhah, A.N. Azadani

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BioTester

2016

Constitutive description of human femoropopliteal artery aging

A. Kamenskiy, A. Seas, P. Deegan, W. Poulson, E. Anttila, S. Sim, A. Desyatova, J. MacTaggart

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MicroSquisher

2016

Delivery of Human Adipose Stem Cells Spheroids into Lockyballs

K.R. Silva, R.A. Rezende, F.D.A.S. Pereira, P. Gruber, M.P. Stuart, A. Ovsianikov, K. Brakke, V. Kasyanov, J.V.L. da Silva, J.M. Granjeiro, L.S. Baptista, V. Mironov

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BioTester

2016

Deposition of a hydrophilic nanocomposite-based coating on a silicone hydrogel through a laser process to minimize UV exposure and bacterial contamination

G. Huang, W. H. Tse, J. Zhang

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UniVert

2016

Development of an infusion bioreactor for the accelerated preparation of decellularized skeletal muscle scaffolds

B. M. Kasukonis, J.T. Kim, T.A. Washington, J.C. Wolchok

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MicroSquisher

2016

Direct Production of Human Cardiac Tissues by Pluripotent Stem Cell Encapsulation in Gelatin Methacryloyl

P. Kerscher, J.A. Kaczmarek, S.E. Head, M. Brazel, W. Seeto, S. Bhattacharya, J. Kim, V. Suppiramaniam, E.A. Lipke

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BioTester

2016

Improved Geometry of Decellularized Tissue Engineered Heart Valves to Prevent Leaflet Retraction

B. Sanders, S. Loerakker, E.S. Fioretta, D.J.P. Bax, A. Driessen-Mol, S.P. Hoerstrup, F.P.T. Baaijens

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BioTester

2016

Inflation and bi-axial tensile testing of healthy porcine carotid arteries

R.W. Boekhoven, M.F.J. Peters, M.C.M. Rutten, M.R. van Sambeek, F.N. van de Vosse, R.G.P Lopata

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UniVert

2016

Material Properties from Air Puff Corneal Deformation by Numerical Simulations on Model Corneas

N. Bekesi, C. Dorronsoro, A. de la Hoz, S. Marcos

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MicroSquisher

2016

Mineral particles modulate osteo-chondrogenic differentiation of embryonic stem cell aggregates

Y. Wang, X. Yu, C. Baker, W.L. Murphy, T.C. McDevitt

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BioTester

2016

Modulation of collaen fiber orientation by strain-controlled enzymatic degradation

S. Ghazanfari, A. Dressen-Mol, C.V.C. Bouten, F.P.T. Baaijens

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BioTester

2016

Nanocomposited coatings produced by laser-assisted process to prevent silicone hydrogels from protein fouling and bacterial contamination

G. Huang, Y. Chen, J. Zhang

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BioTester

2016

Patient Specific Vascular Benchtop Models for Development and Validation of Medical Devices for Minimally Invasive Procedures

M. Kvasnytsia, N. Famaey, M. Bohm, E. Verhoelst

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BioTester

2016

Peak stress in the annulus fibrosis under cyclic biaxial tensile loading

C.E. Gooyers, J.P. Callaghan

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MicroSquisher

2016

PEG-fibrinogen Hydrogels for Three-dimensional Breast Cancer Cell Culture

S. Pradhan, I. Hassani, W.J. Seeto, E. A. Lipke

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BioTester

2016

Phototactic guidance of a tissue-engineered soft-robotic ray

S-J. Park, M. Gazzola, K.S. Park, S. Park, V. Di Santo, E.L Blevins, J.U. Lind, P.H. Campbell, S. Dauth, K.K. Parker

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BioTester

2016

Planar biaxial testing of heart valve cusp replacement biomaterials: Experiments, theory and material constants

M.R. Labrosse, R. Jafar, J.Ngu, M. Boodhwani

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BioTester

2016

Planar biaxial testing of soft biological tissue using rakes: A critical analysis of protocol and fitting process

H. Fehervary, M. Smoljkic, J.Vander Sloten, N. Famaey

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BioTester

2016

Production of Synthetic, Para-Aramid and Biopolymer Nanofibers by Immersion Rotary Jet-Spinning

G.M. Gonzalez, L.A. MacQueen, J.U. Lind, S.A. Fitzgibbons, C. O. Chantre, I. Huggler, H.M. Golecki, J.A. Goss, K.K. Parker

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BioTester

2016

Quantification of Coupled Stiffness and Fiber Orientation Remodeling in Hypertensive Rat Right-Ventricular Myocardium Using 3D Ultrasound Speckle Tracking with Biaxial Testing

D.W. Park, A. Sebastiani, C.H. Yap, M.A. Simon, K. Kim

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MicroSquisher

2016

Reactive eletrospinning of degradable poly(oligoethylene glycol methacrylate)-based nanofibrous hydrogel networks

F. Xu, H. Sheardown, T. Hoare

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BioTester

2016

The aging disc: using an ovine model to examine age-related differences in the biomechanical properties of the intralamellar matrix of single lamellae

D.M. Stewart, L.A. Monaco, D.E. Gregory

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BioTester

2016

The choice of a constitutive formulation for modeling limb flexion-induced deformations and stresses in the human femoropopliteal arteries of different ages

A. Desyatova, J. MacTaggart, W. Poulson, P. Deegan, C. Lomneth, A. Sandip, A. Kamenskiy

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BioTester

2016

The Effect of Local Hydration Environment on the Mechanical Properties and Unloaded Temporal Changes of Isolated Porcine Annular Samples

K.M. Gruevski, C.E. Gooyers, T. Karakolis, J.P. Callaghan

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UniVert

2016

The global mechanical properties and multi-scale failure mechanics of heterogeneous human stratum corneum

X. Liu, J. Cleary, G.K. German

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BioTester

2015

Adipose derived tissue engineered heart valve

L. Frese, B. Sanders, G.M. Beer, B. Weber, A. Driessen-Mol, F.P.T. Baaijens, S.P. Hoerstrup

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BioTester

2015

Biaxial stress relaxation of semilunar heart valve leaflets during simulated collagen catabolism: effects of collagenase concentration and equibiaxial strain state

S. Huang, H.-Y. S. Huang

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BioTester

2015

Building a better infarct: Modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction

A.P. Voorhees, K.Y. DeLeon-Pennell, Y. Ma, G. V. Halade, A. Yabluchanskiy, R. Padmanabhan, E. Flynn, C.A. Cates, M.L. Lindsey, H.-C. Han

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MicroSquisher

2015

Burr-like, laser-made 3D microscaffolds for tissue spheroid encagement

P. Danilevicius, R.A. Rezende, F.D.A.S. Pereira, A. Selimis, V. Kasyanov, P.Y. Noritomi, J.V.L. da Silva, M.Chatzinikolaidou, M. Farsari, V. Mironov

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BioTester

2015

Corneal collagen cross-linking combined with simulation of femtosecond laser-assisted refractive lens extraction: an ex vivo biomechanical effect evaluation

A.J. Kanellopoulos, M.A. Kontos, S. Chen, G. Asimellis

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BioTester

2015

Development of a biological scaffold engineered using the extracellular matrix secreted by skeletal muscle cells

S.A. Hurd, N.M. Bhatti, A.M. Walker, B.M. Kasukonis, J.C. Wolchok

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UniVert

2015

Development of a biological scaffold engineered using the extracellular matrix secreted by skeletal muscle cells

S. A. Hurd, N.M. Bhatti, A.M. Walker, B.M. Kasukonis, J.C. Wolchok

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BioTester

2015

Development of non-cell adhesive vascular grafts using supramolecular building blocks

G. C. van Almen, H. Talacua, B.D. Ippel, B.B. Mollet, M. Ramaekers, M. Simonet, A.I.P.M. Smits, C.V.C. Bouten, J. Kluin, P.Y.W. Dankers

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BioTester

2015

High-irradiance CXL combined with myopic LASIK: flap and residual stroma biomechanical properties studied ex-vivo

A.J. Kanellopoulos, G. Asimellis, B.Salvador-Culla, J. Chodosh, J.B. Ciolino

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UniVert

2015

High-irradiance CXL combined with myopic LASIK: flap and residual stroma biomechanical properties studied ex-vivo

A. J. Kanelloploulos, G. Asimellis, B. Salvador-Culla, J. Chodosh, J.B. Ciolino

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BioTester

2015

Improved geometry of decellularized tissue engineered heart valves to prevent leaflet retraction

B. Sanders, S. Loerakker, E.S. Fioretta, D.J.P. Bax, A. Driessen-Mol, S.P.Hoerstrup, F.P.T Baaijens

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BioTester

2015

Leaflet stress and strain distributions following incomplete transcatheter aortic valve expansion

M. Abbasi, A.N. Azadani

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BioTester

2015

Methods for using 3-D ultrasound speckle tracking in biaxial mechanical testing of biological tissue samples

C.H. Yap, D.W. Park, D. Dutta, M. Simon, K. Kim

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BioTester

2015

Nanocomposite silicone hydrogels with a laser-assisted surface modification for inhibiting the growth of baterial biofilm

P. Yin, G.B. Huang, W.H. Tse, Y.G. Bao, J. Denstedt, J. Zhang

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BioTester

2015

Regional and depth variability of porcine meniscal mechanical properties through biaxial testing

A. Kahlon, M.B. Hurtig, K.D. Gordon

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BioTester

2015

Superior tissue evolution in slow degrading scaffolds for valvular tissue engineering

M. Brugmans, S. Soekhradj-Soechit, D. van Geemen, M.A.J. Cox, C. Bouten, F.P.T. Baaijens, A. Driessen-Mol

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BioTester

2015

The Biomechanics of Eyelid Tarsus Tissue

M.T. Sun, D. Pham, A.J. O'Conner, J. Wood, R. Casson, D. Selva, J.J. Costi

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BioTester

2014

Cardiac Function of the Naked Mole-Rat: Echophysiological Responses to Working Underground

K.M. Grimes, A. Voorhees, Y.A. Chiao, H-C. Han, M.L. Lindsey, R. Buffenstein

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BioTester

2014

Directional Biomechanical Properties of Porcine Skin Tissue

H-Y. Huang, S. Huang, C.P. Frazier, P.M. Prim, O. Harrysson

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UniVert

2014

Intrastromal Application of Riboflavin for Corneal Crosslinking

T.G. Seiler, I. Fischinger, T. Senfft, G. Schmidinger, T. Seiler

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MicroSquisher

2014

Mesenchymal morphogenesis of embryonic stem cells dynamically modulates the biophysical microtissue niche

M.A. Kinney, R.Saeed, T.C. McDevitt

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BioTester

2014

Modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues

G. Argento, N. de Jonge, S.H.M. Sontjens, C.W.J. Oomens, C.V.C. Bouten, F.P.T. Baaijens

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BioTester

2014

Should a native depth-dependent distribution of human meniscus constitutive components be considered in FEA-models of the knee joint?

J.M. Parraga Quiroga, P. Emmans, W. Wilson, K. Ito, C.C. van Donkelaar

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BioTester

2014

Strain-dependent modulation of macrophage polarization within scaffolds

V. Ballotta, A. Dressen-Mol, C.V.C. Bouten, F.P.T. Baaijens

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BioTester

2014

Structural and mechanical adaptations of right ventrical free wall myocardium to pressure overload

M.R. Hill, M.A. Simon, D. Valdez-Jasso, H.C. Champion, M.S. Sacks

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BioTester

2014

The biaxial biomechanical behavior of adominal aortic aneurysm tissue

S.A. O'Leary, D.A. Healey, E.G. Kavanagh, M.T. Walsh, T.M. McGloughling, B.J. Doyle

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BioTester

2014

The biaxial mechanical behaviour of abdominal aortic aneurysm intraluminal thrombus: Classification of morphology and the determination of layer and region specific properties

S.A. O'Leary, E.G. Kavanagh, P.A. Grace, T.M. McGloughlin, B.J. Doyle

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BioTester

2014

The impact of long term freezing on the mechanical properties of porcine aortic tissue

S. O'Leary, B. Doyle, T. McGloughlin

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BioTester

2014

Vascular Elastography: A Validation Study

R.G.P. Lopata, M.F.J. Peters, J. Nijs, C.W. Oomens, M.C.M. Rutten, F.N. van de Vosse

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BioTester

2013

A Nanocomposite Contact Lens for the Delivery of Hydrophilic Protein Drugs

J. Zhang, R. Bi, W. Hodge, P. Yin, W.H. Tse

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MicroSquisher

2013

Alginate Encapsulation Parameters Influence the Differentiation of Microencapsulated Embryonic Stem Cell Aggregates

Wilson, J.L., Ali Naijia, M., Saeed, R., McDevitt, T.C.

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BioTester

2013

Comparison of methods used to measure the thickness of soft tissues and their influence on the evaluation of tensile stress

S.A. O'Leary, B.J. Doyle, T.M. McGloughlin

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BioTester

2013

Corneal resistance to shear force after UVA-riboflavin cross-linking

A.P. Sondergaard, A. Ivarsen, J. Hjortdal

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BioTester

2013

In vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells

B. Weber, D. Kehl, U. Bleul, S. Sammut, L. Frese, A. Ksiazek, L Behr, J. Achermann, G. Stranzinger, J. Robert, B. Sanders, M. Sidler, C.E. Brokopp, S.T. Proulx, T. Frauenfelder, R. Schoenauer, M.Y.Emmert, V. Falk, S.P.Herstrup

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BioTester

2013

Mechanical Analysis of Ovine and Pediatric Pulmonary Artery for Heart Valve Stent Design

M.S. Cabrera, C.W.J. Oomens, C.V.C. Bouten, A.J.J.C. Bogers, S.P. Hoerstrup, F.P.T. Baaijens

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BioTester

2013

Mechanics of the pulmonary valve in the aortic position

A.L.F. Soares, D. van Geeman, A.J. van den Bogaerdt, C.W.J. Oomens, C.V.C. Bouten, F.P.T. Baaijens

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BioTester

2013

Reduction of Stromal Swelling Pressure after UVA-Riboflavin Cross-Linking

A.P. Sondergaard, A. Ivarsen, J. Hjortdal

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BioTester

2012

A Murine Experimental Model for the Mechanical Behavior of Viable Right-Ventricular Myocardium

D. Valdez-Jasso, M.A. Simon, H.C. Champion, M.S. Sacks

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BioTester

2012

An Examination of the Mechanical Properties of the Annulus Fibrosus: The Effect of Vibration on the Intra-lamellar Matrix Strength

Diane Gregory, J. Callaghan

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BioTester

2012

Application of Simple Biomechanical and Biochemical Tests to Heart Valve Leaflets: Implications for Heart Valve Characterization and Tissue Engineering

H-Y. Huang, B.N. Balhouse, S. Huang

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BioTester

2012

Biomechanical Properties of the Transverse Carpal Ligament Under Biaxial Strain

Michael Holmes, S. Howarth, J. Callaghan, P. Keir

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BioTester

2012

Multi-Scale Mechanical Characterization of Scaffolds for Heart Valve Tissue Engineering

G. Argento, M. Simonet, C.W.J. Oomens, F.P.T. Baaijens

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MicroSquisher

2012

Stiffening of Human Mesenchymal Stem Cell Spheroid Mircoenvironments Induced By Incorporation of Gelatin Microparticles

P. R. Baraniak, M.T. Cooke, R. Saeed, M.A. Kinney, K.M. Fridley, T.C. mcDevitt

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BioTester

2011

A Comparison of Uniaxial and Biaxial Mechanical Properties of the Annulus Fibrosus: A Porcine Model

Diane Gregory, J. Callaghan

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BioTester

2011

Does Vibration Influence the Initiation of Intervertebral Disc Herniation

Diane Gregory, J. Callaghan

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BioTester

2011

Novel Lap Test Determines the Mechanics of Delamination Between Annular Lamellae of the Intervertebral Disc

D. Gregory, J. Veldhuis, C. Horst, W. Brodland, J. Callaghan

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BioTester

2011

Surfactant Assisted Incorporation of Single-Walled Carbon Nanotubes Into a Chitosan-polyvinylpyrrolidone Polymer

T. Davis, J. Zhang, J.E. Herrera

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BioTester

2010

An Examination of the Influence of Strain Rate on Subfailure Mechanical Properties of the Annulus Fibrosus

D. Gregory, J. Callaghan

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BioTester

2010

Biaxial Mechanical Testing of Human Sclera

A. Eilaghi, J. Flanagan, I. Tertinegg, C. Simmons, W. Brodland, R. Ethier

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BioTester

2010

Effects of Sclera Stiffness on Biomechanics of the Optic Nerve Head in Glaucoma

A. Eilaghi

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BioTester

2010

Effects of Sclera Stiffness Properties on Optic Nerve Head Biomechanics

A. Eilaghi, J. Flanagan, C. Simmons, R. Ethier

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MicroSquisher

2009

Cellular Interfacial and Surface Tensions Determined From Aggregate Compression Tests Using a Finite Element Model. HFSP Journal

Brodland, G.W., Yang, J., Sweny, J.

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BioTester

2009

Fabrication of Nanofiber Reinforced Protein Structures for Tissue Engineering

V. Beachley, X. Wen

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BioTester

2009

Strain Uniformity in Biaxial Specimens is Highly Sensitive to Attachment Details

A. Eilaghi, J. Flanagan, G.W. Brodland, R. Ethier

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BioTester

2009

The Influence of the Tensile Material Properties of Single Annulus Fibrosus Lamellae and the Interlamellar Matrix Strength on Disc Herniation and Progression

D. Gregory

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