供应athens research & technologyBrand,16-16-012020Item#,Athens Research & Technology；16-16-012020；Antithrombin III, Human Plasma

Athens Research & Technology；16-16-012020；Antithrombin III, Human Plasma

型号:16-16-012020
联系人:程园
联系电话:18611717737
品牌:athens research & technology

Athens Research & Technology 公司位于美国乔治亚州雅典市，从1986年以来一直于纯化高纯度，高活性的人类蛋白质和开发这些蛋白的多克隆抗血清。我们的常规产品包括丝氨酸蛋白酶、蛋白酶抑制剂、中性粒细胞酶、载脂蛋白、脂蛋白，血小板蛋白、转铁蛋白、免疫球蛋白等。二十年多年来，世界各地的研究人员都在使用我们公司的产品。在炎症、状动脉疾病、自身免疫性疾病、癌症、老年痴呆症等等研究的主要科学出版物中都能看到引用我们公司的产品。
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Synonym: ATIII, Antithrombin, AT, Factor Xa inhibitor, Heparin cofactor

MW: 58,000
Extinction Coefficient: 0.65

Lyophilized from 50 mM Tris-HCl, pH 8.0, with 150 mM NaCl.

Storage: -20°C

Purified Native Human Antithrombin III, Human Plasma
Bulk Qty Available.

Antithrombin III is found in normal serum at 15 mg per 100 ml. Found at higher levels in plasma than in serum because of complexing with thrombin during coagulation. Functions in the inhibition of the proteolytic enzymes involved in blood coagulation and fibrinolysis, including factor Xa, plasmin, thrombin, and trypsin. Potency is strongly enhanced by heparin. Clinically, reduced levels are indicative of hypercoagulability.

Purity: >=95% by SDS-PAGE

Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research use only.

Product Citation:

Perera, Natascha C., Oliver Schilling, Heike Kittel, Walter Back, Elisabeth Kremmer, and Dieter E. Jenne. "NSP4, an elastase-related protease in human neutrophils with arginine specificity. Proceedings of the National Academy of Sciences 109, no. 16 (2012): 6229-6234.

Guo C, et al.
High-resolution probing heparan sulfate–antithrombin interaction on a single endothelial cell surface: single-molecule AFM studies.
Phys Chem Chem Phys. 2015 May 28;17(20):13301-6. doi: 10.1039/c5cp01305d.

Tafaleng EN, et al.
Induced pluripotent stem cells model personalized variations in liver disease resulting from α1-antitrypsin deficiency.
Hepatology. 2015 Jul;62(1):147-57. doi: 10.1002/hep.27753. Epub 2015 Apr 13.