Athens Research & Technology;16-16-012901;Alpha 2 Antiplasmin, Human Plasma

品牌:athens research & technology

Athens Research & Technology 公司位于美国乔治亚州雅典市,从1986年以来一直致力于纯化高纯度,高活性的人类蛋白质和开发这些蛋白的多克隆抗血清。我们的常规产品包括丝氨酸蛋白酶、蛋白酶抑制剂、中性粒细胞酶、载脂蛋白、脂蛋白,血小板蛋白、转铁蛋白、免疫球蛋白等。二十年多年来,世界各地的研究人员都在使用我们公司的产品。在炎症、冠状动脉疾病、自身免疫性疾病、癌症、老年痴呆症等等研究的主要科学出版物中都能看到引用我们公司的产品。
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MW: 70,000
Extinction Coefficient: 0.703

Lyophilized from 20 mM Bis-Tris, pH 6.4, with 200 mM NaCl.

Storage: -20°C

Alpha 2 Antiplasmin, Human Plasma (Coagulation Factor). Buy direct from the manufacturer. 
Bulk Qty Available. Same day shipping.

Efficiently inhibits the plasminogen-activator-induced lysis of fibrin clots. Found in plasma at about 70 ug per ml. Alpha-antiplasmin-deficiency is a rare coagulation disorder which allows unrestrained fibrinolytic activity. Individuals with this condition may receive therapeutic A2AP prior to surgery to prevent postoperative hemorrhaging.

Purity: >=95% by SDS-PAGE

Specific Activity: >= 5.0 U/mg

Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research use only.

Product Citation:
Zimmerman, Thomas P., Valery Novokhatny, Shan Jiang, and James D. Colandene. "Reversibly inactivated acidified plasmin composition." U.S. Patent Application 13/761,684, filed February 7, 2013.

Singh S, Houng A, Reed GL.
Releasing the Brakes on the Fibrinolytic System in Pulmonary Emboli.
Circulation. 2017 Mar 14;135(11):1011-1020. doi: 0.1161/CIRCULATIONAHA.116.024421. Epub 2016 Dec 27