LRRK2-IN-1

Availability: In Stock
Biological Description:
LRRK2-IN-1 is a cell-permeable, ATP competitive, potent, and selective LRRK2 inhibitor. IC50 is 13 nM, 6 nM, and 2.45 μM for wild type, G2019S mutant, and drug resistant A2016T mutant LRRK2, respectively.
IC50 Value: 13 nM (wild type); 6 nM (G2019S mutant); 2.45 μM (drug resistant A2016T mutant LRRK2)
Target: LRRK2; Mutant LRRK2
LRRK2-IN-1 is useful in treatment of Parkinson's disease.

Purity: >98%

Molecular formula: C₃₁H₃₈N₈O₃

Molecular Weight: 570.69

Storage Instructions: Two years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO