Mupirocin lithium salt is a carboxylic acid isolated from Pseudomonas fluorescens. When at lower concentrations, it exhibits bacteriostatic properties, while exhibiting bactericidal properties at higher concentrations. It targets gram-positive bacteria such as methicillin-resistant Staphylococcus aureus (MRSA). Mupirocin lithium salt has been used to study mupirocin resistance in Mycoplasma bacteria.

Mupirocin works by inhibiting isoleucyl-tRNA synthetase (IRS), ultimately causing inhibition of protein and RNA synthesis. Mupirocin lithium salt is freely soluble in water.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Mupirocin Lithium Salt

MOLECULAR BIOLOGY GRADE

Formula: C₂₆H₄₃LiO₉

MW: 506.56 g/mol

Storage/Handling: Store at 2-8°C.

PubChem Chemical ID: 71311795