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Miniature
Incubator for mechanical microscopes stages to use with slides and
Petri dishes, TC-MIS
Designed
for long-term live cell imaging and time-lapsed microscopy. Can be used with
Petri dishes, chambered coverglasses, coverslip holders and
glass bottom dishes, both 35 and 50mm. Incorporates luer-lock ports for gas mixture (to control CO2
or hypoxia), inside
reservoir for water to control humidity, and heated cover (purchased separately), to
prevent condensation. Built-in multiple ports for tubing and
accessories (probes and sensors). Requires a temperature controller.
Incorporates STAGE sensor for stable temperature control, and can be
used with optional BATH probe to monitor inside temperature. Fits any microscope
(specify microscope model when ordering, ships installed on the microscope adapter;
some (Zeiss for example) microscopes
need a recessed down insert - type K - and a different
incubator with 160x110mm foot print).
Can be upgraded with a heated lid with
openings
to access cells with micro-injection tools to perform cell manipulation.
Can be upgraded with an objective heater for immersion optics.
For use with long-distance objectives, select TC-MIS-65x75-HB incubator with closed 1mm heated glass bottom, which allows you to use
both slides, Petri dishes and custom devices.
Can be used with multi-channel solution switch and perfusion systems.
An optional set of adjustable tubing
holders MH-MIS allows you to position inflow and outflow tubing
for continuous media exchange.
All incubators require a lid purchased separately. Click on images to enlarge.
Low-Profile configurations ( /L)
are only 25mm high and can be used with microscope condensers that require
low vertical positioning to obtain bright-field images with Phase-contrast
or DIC optics.
Incorporates two ports for CO2 input and to replenish water to control humidity inside.
Although this configuration provides two ports that can be used for tubing, it is not recommended for perfusion applications
due to reduced vertical clearance inside.
Incubator with 22x46mm bottom window, TC-MIS-20x46/L. Can be used with 50mm dishes and chambers, slides/coverglasses,
and, in combination with 50mm reducing insert TC-PA50 (-C, -N, -F, -W), with 35 dishes and coverslip holders CSC/UTIC.
Incubator with 35mm bottom window for use with
Petri dishes and coverslip holder CSC and UTIC, TC-MIS-35/L.
Has the 35mm bottom aperture open
for easy access with immersion optics. Can be also used with 35mm dishes and coverslip holders CSC and UTIC.
Incubator with 15mm bottom window for use with
Petri dishes, TC-MIS-15/L.
Provides better heat distribution from the bottom due to reduced 15mm aperture. Might require reducing insert TC-PA-C/F/N/W for different brands
of Petri dishes.
Incubator with 11mm bottom window for use with
Petri dishes, TC-MIS-11/L.
Provides better heat distribution from the bottom due to reduced 11mm aperture. Might require reducing insert TC-PA-C/F/N/W for different brands
of Petri dishes.
Incubator with 45mm bottom
aperture for use with 50mm Petri dishes and chambers, TC-MIS-45/L.
Incubator with 30mm bottom
aperture for use with 50mm Petri dishes and chambers, TC-MIS-30/L.
Provides better heat distributionfrom the bottom.
If used with 50mm reducing insert TC-PA50,
can be also used with 35nn dishes and coverslip holders CSC and UTIC.
Incubator with
80x70mm glass 1mm thick heated closed bottom,
TC-MIS-65x75-HB/L.
For use
with long-distance objectives only. Has the whole bottom closed with 1mm glass to provide uniform heating.
Can be used custom devices and UTIC chambers.
Specifications: |
Stability: | 0.1癈 |
Outside dimensions: | 110 x 110 mm; 34mm from sample
plane to the top cover (25mm clearance for low-profile
configuration) |
Optical aperture (on
the bottom): | 20x46mm,
65x75mm, 40, 35, 30, 15 and 11mm diameter |
Use with: | 50mm and
35mm glass bottom dishes, 1x3in. coverglasses/slides, coverslip holders CSC,
custom devices, and UTIC chambers |
Condensation free lid: | Uses
a built-in temperature sensor to connect independently to
the second channel of the temperature controllers; 70x70mm optical window |
CO2 port: | Luer-lock connector to a source of gas mixture. |
Water reservoir: | Controls humidity. Can be replenished through outside ports. |
Media exchange and perfusion: |
Multiple sealed inflow/outflow ports, a set of
optional adjustable tubing holders to position inflow and outflow tubing inside sample chambers. |
Perfusion cover low-profile, with perfusion ports and tubing,
FLOW-LOW
For use inside TC-MIS incubators. Includes x2 sets of tubing
to fit into reduced inflow and outflow ports, which extend to the bottom of a
Petri dish.
Tubing has a luer-lock fitting attached, and can be put through side ports of the incubator.
This cover, if placed on a standard Petri dish, forms a flow cell.
The high optical quality glass window on top is 12mm diameter.
Can be used in combination with PDI insert to provide laminar flow.
Can be used
to replenish media around your samples during time-lapse imaging. Can be sterilized with
ethanol solution or autoclaved (100癈 max).
Click on catalog numbers below to purchase online.
Sample publications:
3
Bacillus subtilis chromosome organization oscillates between two distinct patterns.
September 2, 2014 vol. 111 no. 35;
2
Molecular Architecture of Synaptic Actin Cytoskeleton in Hippocampal Neurons Reveals a Mechanism of Dendritic Spine Morphogenesis.
Mol. Biol. Cell January 1, 2010 vol. 21 no. 1 165-176;
1
Evolution of Network Synchronization during Early Epileptogenesis Parallels Synaptic Circuit Alterations.
The Journal of Neuroscience, 8 July 2015, 35(27): 9920-9934;
Required accessories: temperature controller,
microscope adapter,
CO2 controller.
Optional accessories: objective heater,
perfusion system and accessories,
flow control.
Download PDF manual.
Download PDF catalog.
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Bioscience Tools
ph: 1-010-6759703
fax: 010-6759703
email: chengyuan@bio-goods.com
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PRICES AND OPTIONS |
TC-MIS-LID |
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Lid for Miniature Incubator TC-MIS
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TC-MIS-INJECT |
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Miniature Incubators Lid for micro-injection and cell manipulation
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TC-MIS-20x46 |
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Miniature Incubator for Glass Coverglass, Slides and dishes, 20x46mm bottom
aperture
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TC-MIS-20x46-L |
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Low-profile Miniature Incubator for Glass Coverglass, Slides and dishes, 20x46mm bottom
aperture
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TC-MIS-45 |
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Miniature Incubator for 50mm glass bottom dishes, 45mm bottom
aperture
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TC-MIS-45-L |
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Low-profile Miniature Incubator for 50mm glass bottom dishes, 45mm bottom
aperture
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TC-MIS-30 |
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Miniature Incubator for 50mm glass bottom dishes, 30mm bottom
aperture
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TC-MIS-30-L |
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Low-profile Miniature Incubator for 50mm glass bottom dishes, 30mm bottom
aperture
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TC-MIS-35 |
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Miniature Incubator for 35mm Petri dishes and coverslip holders CSC and UTIC, 35mm bottom
aperture
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TC-MIS-35-L |
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Low-profile Miniature Incubator for 35mm
Petri dishes and coverslip holders CSC and UTIC, 35mm bottom aperture
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TC-MIS-15 |
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Miniature Incubator for 35mm Petri and glass bottom dishes, 15mm bottom
aperture
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TC-MIS-15-L |
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Low-profile Miniature Incubator for 35mm
Petri and glass bottom dishes, 15mm bottom aperture
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TC-MIS-11 |
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Miniature Incubator for 35mm petri and glass bottom dishes, 11mm bottom
aperture
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TC-MIS-11-L |
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Low-profile Miniature Incubator for 35mm
Petri and glass bottom dishes, 11mm bottom aperture
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TC-MIS-65x75-HB |
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Incubator with 65x75mm glass window, 1mm thick,
heated closed bottom for use with custom devices
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TC-MIS-65x75-HB-L |
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Low-profile Incubator with 65x75mm glass window,
1mm thick, heated closed bottom for use with custom devices
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IMA-74 |
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Microscope Adapter for Miniature Incubators.
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TC-PA50 |
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50mm reducing adapter for 35mm dishes, to use
with TC-MIS-20x46, TC-MIS40 and TC-MIS-30 models. |
TC-PA-C |
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Petri Dish Adapter -reducing rings- for Corning and Mattek dishes |
TC-PA-N |
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Petri Dish Adapter -reducing rings- for Nunc dishes |
TC-PA-F |
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Reducing adapter -reducing rings-, for FluoroDishes.
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TC-PA-G |
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Reducing adapter -reducing rings-, for Greiner Bio-One dishes, glass bottom
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TC-PA-W |
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Petri Dish Adapter -reducing rings- for Willco dishes |
MH-MIS |
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Set of miniature adjustable tubing and sensor holders, x3, includes 4-40 threaded posts |
FLOW-LOW |
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Perfusion cover low-profile, with perfusion ports and tubing |
PDI |
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Low Profile Chamber-Insert for Petri dish |
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