世联博研,世联博研(北京)科技有限公司—专注生物力学和3D生物打印服务等再生医学服务

keywordStem cell 世联博研,世联博研(北京)科技有限公司—专注生物力学和3D生物打印服务等再生医学服务

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产品编号	产品名称	产地	价格/规格
BioTester	an investigation of regional variations in the biaxial mechanical properties and stress relaxation behaviors of porcine atrioventricular heart valve leaflets, strain effects on collagen proteolysis in heart valve tissues, comparison of biomechanical properties and microstructure of trabeculae carneae, papillary muscles, and myocardium in the human heart, rate-dependency of the mechanical behavior of semilunar heart valves under biaxial deformation, an investigation of layer-specific tissue biomechanics of porcine atrioventricular valve anterior leaflets, the degradation and performance of electrospun supramolecular vascular scaffolds examined upon in vitro enzymatic exposure, mechanical damage characterization in human femoropopliteal arteries of different ages, cyclic strain affects macrophage cytokine secretion and extracellular matrix turnover in electrospun scaffolds, image-based analysis of uniaxial ring test for mechanical characterization of soft materials and biological tissues, mechanical properties of autologous pericardium change with fixation time: implications for valve reconstruction, tissue level mechanical properties and extracellular matrix investigation of the bovine jugular venous valve tissue, regional biaxial mechanical data of the mitral and tricuspid valve anterior leaflets, mechanics of the tricuspid valve-from clinical diagnosis/treatment, in-vivo and in-vitro investigations, to patient-specific biomechanical modeling., an investigation of the glycosaminoglycan contribution to biaxial mechanical behaviours of porcine atrioventricular heart valve leaflets, macrophage-driven biomaterial degradation depends on scaffold microarchitecture, the effect of axial torsion on the mechanical properties of the annulus fibrosus, integration of polarized spatial frequency domain imaging (psfdi) with a biaxial mechanical testing system for dynamic quantification of collagen architecture in soft collagenous tissues, an integrated opto-mechanical system for quantification of dynamic microstructure and mechanics of heart valve tissues, effects of longitudinal pre-stretch on the mechanics of human aorta before and after thoracic endovascular aortic repair (tevar) in trauma patients, human in vitro model of material-driven vascular regeneration reveals how cyclic stretch and shear stress differentially modulate inflammation and tissue formation, some effects of different constitutive laws on fsi simulation for the mitral valve, biomechanical restoration potential of pentagalloyl glucose after arterial extracellular matrix degeneration, an investigation of the effect of freezing storage on the biaxial mechanical properties of excised porcine tricuspid valve anterior leaflets, a detailed mechanical and microstructural analysis of the ovine tricuspid valve leaflets, the regional-dependent biaxial behavior of young and aged mouse skin: a detailed histomechanical characterization, residual strain analysis, and constitutive model, biaxial mechanical behavior of bovine saphenous venous valve leaflets, prevalence of calcification in human femoropopliteal arteries and its association with demographics, risk factors, and arterial stiffness, comparison of corneal biomechanics after myopic small-incision lenticule extraction compared to lasik: an ex vivo study, dehiscence of patch augmentation of a left-sided atrioventricular valve related to strenuous isometric exercise: case report and failure analysis, puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization, biomechanical evaluation of a personalized external aortic root support applied in the ross procedure, polydopamine as sizing on carbon fiber surfaces for enhancement of epoxy laminated composites, comparison of in vivo vs. ex situ obtained material properties of sheep common carotid artery, soy protein/cellulose nanofiber scaffolds mimicking skin extracellular matrix for enhanced wound healing, new findings confirm the viscoelastic behaviour of the inter-lamellar matrix of the disc annulus fibrosus in radial and circumferential directions of loading, 3d printed, controlled release, tritherapeutic tablet matrix for advanced anti-hiv-1 drug delivery, computational modeling guides tissue-engineered heart valve design for long-term in vivo performance in a translational sheep model, pressure-induced end-plate fracture in the porcine spine: is the annulus fibrosus susceptible to damage?, dual electrospun supramolecular polymer systems for selective cell migration, regional mechanical and biochemical properties of the porcine cortical meninges, new insights into the viscoelastic and failure mechanical properties of the elastic fiber network of the inter-lamellar matrix in the annulus fibrosus of the disc, initial scaffold thickness affects the emergence of a geometrical and mechanical equilibrium in engineered cardiovascular tissues, development of an improved parameter fitting method for planar biaxial testing using rakes, the biomechanics of the inter-lamellar matrix and the lamellae during progression to lumbar disc herniation: which is the weakest structure?, mechanically robust cryogels with injectability and bioprinting supportability for adipose tissue engineering, biomechanical characterization of human dura mater, 3d printed, pva–paa hydrogel loaded-polycaprolactone scaffold for the delivery of hydrophilic in-situ formed sodium indomethacin, a transverse isotropic constitutive model for the aortic valve tissue incorporating rate-dependency and fibre dispersion: application to biaxial deformation, decoupling the effect of shear stress and stretch on tissue growth and remodeling in a vascular graft, an investigation of the anisotropic mechanical properties and anatomical structure of porcine atrioventricular heart valves, biaxial mechanical data of porcine atrioventricular valve leaflets, biaxial mechanical characterization of atrioventricular heart valves, biaxial experimental and analytical characterization of a dielectric elastomer, biaxial mechanical properties of bovine jugular venous valve leaflet tissues, comparison of femoropopliteal artery stents under axial and radial compression, axial tension, bending, and torsion deformations, constitutive modeling of human femoropopliteal artery biaxial stiffening due to aging and diabetes, constitutive modeling of jugular vein-derived venous valve leaflet tissues, design and characterization of a hyperelastic tubular soft composite, in situ heart valve tissue engineering using a bioresorbable elastomeric implant – from material design to 12 months follow-up in sheep, jetvalve: rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement, limb flexion-induced twist and associated intramural stresses in the human femoropopliteal artery, mechanically robust electrospun hydrogel scaffolds crosslinked via supramolecular interactions, nondestructive mechanical characterization of developing biological tissues using inflation testing, on the influence of wall calcification and intraluminal thrombus on prediction of abdominal aortic aneurysm rupture, paraspinal muscle passive stiffness remodels in direct response to spine stiffness: a study using the ent1-deficient mouse, tensile behaviour of individual fibre bundles in the human lumbar anulus fibrosus, urinary bladder versus gastrointestinal tissue: a comparative study of their biomechanical properties for urinary tract reconstruction, a comparison between porcine, ovine, and bovine intervertebral disc anatomy and single lamella annulus fibrosis tensile properties, acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro, age-dependent changes in geometry, tissue composition and mechanical properties of fetal to adult cryopreserved human heart valves, are adipose-derived stem cells cultivated in human platelet lysate suitable for heart valve tissue engineering, biaxial quantification of deep layer transverse carpal ligament elastic properties by sex and region, biomechanical characterization of ascending aortic aneurysms, biomechanical properties and microstructure of heart chambers: a paired comparison study in an ovine model, characterization of three-dimensional anisotropic heart valve tissue mechanical properties using inverse finite element analysis, constitutive description of human femoropopliteal artery aging, deposition of a hydrophilic nanocomposite-based coating on a silicone hydrogel through a laser process to minimize uv exposure and bacterial contamination, improved geometry of decellularized tissue engineered heart valves to prevent leaflet retraction, inflation and bi-axial tensile testing of healthy porcine carotid arteries, modulation of collaen fiber orientation by strain-controlled enzymatic degradation, nanocomposited coatings produced by laser-assisted process to prevent silicone hydrogels from protein fouling and bacterial contamination, patient specific vascular benchtop models for development and validation of medical devices for minimally invasive procedures, peak stress in the annulus fibrosis under cyclic biaxial tensile loading, phototactic guidance of a tissue-engineered soft-robotic ray, planar biaxial testing of heart valve cusp replacement biomaterials: experiments, theory and material constants, planar biaxial testing of soft biological tissue using rakes: a critical analysis of protocol and fitting process, production of synthetic, para-aramid and biopolymer nanofibers by immersion rotary jet-spinning, quantification of coupled stiffness and fiber orientation remodeling in hypertensive rat right-ventricular myocardium using 3d ultrasound speckle tracking with biaxial testing, the aging disc: using an ovine model to examine age-related differences in the biomechanical properties of the intralamellar matrix of single lamellae, the choice of a constitutive formulation for modeling limb flexion-induced deformations and stresses in the human femoropopliteal arteries of different ages, the effect of local hydration environment on the mechanical properties and unloaded temporal changes of isolated porcine annular samples, adipose derived tissue engineered heart valve, biaxial stress relaxation of semilunar heart valve leaflets during simulated collagen catabolism: effects of collagenase concentration and equibiaxial strain state, building a better infarct: modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction, corneal collagen cross-linking combined with simulation of femtosecond laser-assisted refractive lens extraction: an ex vivo biomechanical effect evaluation, development of non-cell adhesive vascular grafts using supramolecular building blocks, high-irradiance cxl combined with myopic lasik: flap and residual stroma biomechanical properties studied ex-vivo, leaflet stress and strain distributions following incomplete transcatheter aortic valve expansion, methods for using 3-d ultrasound speckle tracking in biaxial mechanical testing of biological tissue samples, nanocomposite silicone hydrogels with a laser-assisted surface modification for inhibiting the growth of baterial biofilm, regional and depth variability of porcine meniscal mechanical properties through biaxial testing, superior tissue evolution in slow degrading scaffolds for valvular tissue engineering, the biomechanics of eyelid tarsus tissue, cardiac function of the naked mole-rat: echophysiological responses to working underground, directional biomechanical properties of porcine skin tissue, modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues, should a native depth-dependent distribution of human meniscus constitutive components be considered in fea-models of the knee joint?, strain-dependent modulation of macrophage polarization within scaffolds, structural and mechanical adaptations of right ventrical free wall myocardium to pressure overload, the biaxial biomechanical behavior of adominal aortic aneurysm tissue, the biaxial mechanical behaviour of abdominal aortic aneurysm intraluminal thrombus: classification of morphology and the determination of layer and region specific properties, the impact of long term freezing on the mechanical properties of porcine aortic tissue, vascular elastography: a validation study, a nanocomposite contact lens for the delivery of hydrophilic protein drugs, comparison of methods used to measure the thickness of soft tissues and their influence on the evaluation of tensile stress, corneal resistance to shear force after uva-riboflavin cross-linking, in vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells, mechanical analysis of ovine and pediatric pulmonary artery for heart valve stent design, mechanics of the pulmonary valve in the aortic position, reduction of stromal swelling pressure after uva-riboflavin cross-linking, a murine experimental model for the mechanical behavior of viable right-ventricular myocardium, an examination of the mechanical properties of the annulus fibrosus: the effect of vibration on the intra-lamellar matrix strength, application of simple biomechanical and biochemical tests to heart valve leaflets: implications for heart valve characterization and tissue engineering, biomechanical properties of the transverse carpal ligament under biaxial strain, multi-scale mechanical characterization of scaffolds for heart valve tissue engineering, a comparison of uniaxial and biaxial mechanical properties of the annulus fibrosus: a porcine model, does vibration influence the initiation of intervertebral disc herniation, novel lap test determines the mechanics of delamination between annular lamellae of the intervertebral disc, surfactant assisted incorporation of single-walled carbon nanotubes into a chitosan-polyvinylpyrrolidone polymer, an examination of the influence of strain rate on subfailure mechanical properties of the annulus fibrosus, biaxial mechanical testing of human sclera, effects of sclera stiffness on biomechanics of the optic nerve head in glaucoma, effects of sclera stiffness properties on optic nerve head biomechanics, fabrication of nanofiber reinforced protein structures for tissue engineering, strain uniformity in biaxial specimens is highly sensitive to attachment details, the influence of the tensile material properties of single annulus fibrosus lamellae and the interlamellar matrix strength on disc herniation and progression, functional arrays of human pluripotent stem cell-derived cardiac microtissues,a	cellscale	李先生
BioTester	an investigation of regional variations in the biaxial mechanical properties and stress relaxation behaviors of porcine atrioventricular heart valve leaflets, strain effects on collagen proteolysis in heart valve tissues, comparison of biomechanical properties and microstructure of trabeculae carneae, papillary muscles, and myocardium in the human heart, rate-dependency of the mechanical behavior of semilunar heart valves under biaxial deformation, an investigation of layer-specific tissue biomechanics of porcine atrioventricular valve anterior leaflets, the degradation and performance of electrospun supramolecular vascular scaffolds examined upon in vitro enzymatic exposure, mechanical damage characterization in human femoropopliteal arteries of different ages, cyclic strain affects macrophage cytokine secretion and extracellular matrix turnover in electrospun scaffolds, image-based analysis of uniaxial ring test for mechanical characterization of soft materials and biological tissues, mechanical properties of autologous pericardium change with fixation time: implications for valve reconstruction, tissue level mechanical properties and extracellular matrix investigation of the bovine jugular venous valve tissue, regional biaxial mechanical data of the mitral and tricuspid valve anterior leaflets, mechanics of the tricuspid valve-from clinical diagnosis/treatment, in-vivo and in-vitro investigations, to patient-specific biomechanical modeling., an investigation of the glycosaminoglycan contribution to biaxial mechanical behaviours of porcine atrioventricular heart valve leaflets, macrophage-driven biomaterial degradation depends on scaffold microarchitecture, the effect of axial torsion on the mechanical properties of the annulus fibrosus, integration of polarized spatial frequency domain imaging (psfdi) with a biaxial mechanical testing system for dynamic quantification of collagen architecture in soft collagenous tissues, an integrated opto-mechanical system for quantification of dynamic microstructure and mechanics of heart valve tissues, effects of longitudinal pre-stretch on the mechanics of human aorta before and after thoracic endovascular aortic repair (tevar) in trauma patients, human in vitro model of material-driven vascular regeneration reveals how cyclic stretch and shear stress differentially modulate inflammation and tissue formation, some effects of different constitutive laws on fsi simulation for the mitral valve, biomechanical restoration potential of pentagalloyl glucose after arterial extracellular matrix degeneration, an investigation of the effect of freezing storage on the biaxial mechanical properties of excised porcine tricuspid valve anterior leaflets, a detailed mechanical and microstructural analysis of the ovine tricuspid valve leaflets, the regional-dependent biaxial behavior of young and aged mouse skin: a detailed histomechanical characterization, residual strain analysis, and constitutive model, biaxial mechanical behavior of bovine saphenous venous valve leaflets, prevalence of calcification in human femoropopliteal arteries and its association with demographics, risk factors, and arterial stiffness, comparison of corneal biomechanics after myopic small-incision lenticule extraction compared to lasik: an ex vivo study, dehiscence of patch augmentation of a left-sided atrioventricular valve related to strenuous isometric exercise: case report and failure analysis, puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization, biomechanical evaluation of a personalized external aortic root support applied in the ross procedure, polydopamine as sizing on carbon fiber surfaces for enhancement of epoxy laminated composites, comparison of in vivo vs. ex situ obtained material properties of sheep common carotid artery, soy protein/cellulose nanofiber scaffolds mimicking skin extracellular matrix for enhanced wound healing, new findings confirm the viscoelastic behaviour of the inter-lamellar matrix of the disc annulus fibrosus in radial and circumferential directions of loading, 3d printed, controlled release, tritherapeutic tablet matrix for advanced anti-hiv-1 drug delivery, computational modeling guides tissue-engineered heart valve design for long-term in vivo performance in a translational sheep model, pressure-induced end-plate fracture in the porcine spine: is the annulus fibrosus susceptible to damage?, dual electrospun supramolecular polymer systems for selective cell migration, regional mechanical and biochemical properties of the porcine cortical meninges, new insights into the viscoelastic and failure mechanical properties of the elastic fiber network of the inter-lamellar matrix in the annulus fibrosus of the disc, initial scaffold thickness affects the emergence of a geometrical and mechanical equilibrium in engineered cardiovascular tissues, development of an improved parameter fitting method for planar biaxial testing using rakes, the biomechanics of the inter-lamellar matrix and the lamellae during progression to lumbar disc herniation: which is the weakest structure?, mechanically robust cryogels with injectability and bioprinting supportability for adipose tissue engineering, biomechanical characterization of human dura mater, 3d printed, pva–paa hydrogel loaded-polycaprolactone scaffold for the delivery of hydrophilic in-situ formed sodium indomethacin, a transverse isotropic constitutive model for the aortic valve tissue incorporating rate-dependency and fibre dispersion: application to biaxial deformation, decoupling the effect of shear stress and stretch on tissue growth and remodeling in a vascular graft, an investigation of the anisotropic mechanical properties and anatomical structure of porcine atrioventricular heart valves, biaxial mechanical data of porcine atrioventricular valve leaflets, biaxial mechanical characterization of atrioventricular heart valves, biaxial experimental and analytical characterization of a dielectric elastomer, biaxial mechanical properties of bovine jugular venous valve leaflet tissues, comparison of femoropopliteal artery stents under axial and radial compression, axial tension, bending, and torsion deformations, constitutive modeling of human femoropopliteal artery biaxial stiffening due to aging and diabetes, constitutive modeling of jugular vein-derived venous valve leaflet tissues, design and characterization of a hyperelastic tubular soft composite, in situ heart valve tissue engineering using a bioresorbable elastomeric implant – from material design to 12 months follow-up in sheep, jetvalve: rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement, limb flexion-induced twist and associated intramural stresses in the human femoropopliteal artery, mechanically robust electrospun hydrogel scaffolds crosslinked via supramolecular interactions, nondestructive mechanical characterization of developing biological tissues using inflation testing, on the influence of wall calcification and intraluminal thrombus on prediction of abdominal aortic aneurysm rupture, paraspinal muscle passive stiffness remodels in direct response to spine stiffness: a study using the ent1-deficient mouse, tensile behaviour of individual fibre bundles in the human lumbar anulus fibrosus, urinary bladder versus gastrointestinal tissue: a comparative study of their biomechanical properties for urinary tract reconstruction, a comparison between porcine, ovine, and bovine intervertebral disc anatomy and single lamella annulus fibrosis tensile properties, acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro, age-dependent changes in geometry, tissue composition and mechanical properties of fetal to adult cryopreserved human heart valves, are adipose-derived stem cells cultivated in human platelet lysate suitable for heart valve tissue engineering, biaxial quantification of deep layer transverse carpal ligament elastic properties by sex and region, biomechanical characterization of ascending aortic aneurysms, biomechanical properties and microstructure of heart chambers: a paired comparison study in an ovine model, characterization of three-dimensional anisotropic heart valve tissue mechanical properties using inverse finite element analysis, constitutive description of human femoropopliteal artery aging, deposition of a hydrophilic nanocomposite-based coating on a silicone hydrogel through a laser process to minimize uv exposure and bacterial contamination, improved geometry of decellularized tissue engineered heart valves to prevent leaflet retraction, inflation and bi-axial tensile testing of healthy porcine carotid arteries, modulation of collaen fiber orientation by strain-controlled enzymatic degradation, nanocomposited coatings produced by laser-assisted process to prevent silicone hydrogels from protein fouling and bacterial contamination, patient specific vascular benchtop models for development and validation of medical devices for minimally invasive procedures, peak stress in the annulus fibrosis under cyclic biaxial tensile loading, phototactic guidance of a tissue-engineered soft-robotic ray, planar biaxial testing of heart valve cusp replacement biomaterials: experiments, theory and material constants, planar biaxial testing of soft biological tissue using rakes: a critical analysis of protocol and fitting process, production of synthetic, para-aramid and biopolymer nanofibers by immersion rotary jet-spinning, quantification of coupled stiffness and fiber orientation remodeling in hypertensive rat right-ventricular myocardium using 3d ultrasound speckle tracking with biaxial testing, the aging disc: using an ovine model to examine age-related differences in the biomechanical properties of the intralamellar matrix of single lamellae, the choice of a constitutive formulation for modeling limb flexion-induced deformations and stresses in the human femoropopliteal arteries of different ages, the effect of local hydration environment on the mechanical properties and unloaded temporal changes of isolated porcine annular samples, adipose derived tissue engineered heart valve, biaxial stress relaxation of semilunar heart valve leaflets during simulated collagen catabolism: effects of collagenase concentration and equibiaxial strain state, building a better infarct: modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction, corneal collagen cross-linking combined with simulation of femtosecond laser-assisted refractive lens extraction: an ex vivo biomechanical effect evaluation, development of non-cell adhesive vascular grafts using supramolecular building blocks, high-irradiance cxl combined with myopic lasik: flap and residual stroma biomechanical properties studied ex-vivo, leaflet stress and strain distributions following incomplete transcatheter aortic valve expansion, methods for using 3-d ultrasound speckle tracking in biaxial mechanical testing of biological tissue samples, nanocomposite silicone hydrogels with a laser-assisted surface modification for inhibiting the growth of baterial biofilm, regional and depth variability of porcine meniscal mechanical properties through biaxial testing, superior tissue evolution in slow degrading scaffolds for valvular tissue engineering, the biomechanics of eyelid tarsus tissue, cardiac function of the naked mole-rat: echophysiological responses to working underground, directional biomechanical properties of porcine skin tissue, modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues, should a native depth-dependent distribution of human meniscus constitutive components be considered in fea-models of the knee joint?, strain-dependent modulation of macrophage polarization within scaffolds, structural and mechanical adaptations of right ventrical free wall myocardium to pressure overload, the biaxial biomechanical behavior of adominal aortic aneurysm tissue, the biaxial mechanical behaviour of abdominal aortic aneurysm intraluminal thrombus: classification of morphology and the determination of layer and region specific properties, the impact of long term freezing on the mechanical properties of porcine aortic tissue, vascular elastography: a validation study, a nanocomposite contact lens for the delivery of hydrophilic protein drugs, comparison of methods used to measure the thickness of soft tissues and their influence on the evaluation of tensile stress, corneal resistance to shear force after uva-riboflavin cross-linking, in vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells, mechanical analysis of ovine and pediatric pulmonary artery for heart valve stent design, mechanics of the pulmonary valve in the aortic position, reduction of stromal swelling pressure after uva-riboflavin cross-linking, a murine experimental model for the mechanical behavior of viable right-ventricular myocardium, an examination of the mechanical properties of the annulus fibrosus: the effect of vibration on the intra-lamellar matrix strength, application of simple biomechanical and biochemical tests to heart valve leaflets: implications for heart valve characterization and tissue engineering, biomechanical properties of the transverse carpal ligament under biaxial strain, multi-scale mechanical characterization of scaffolds for heart valve tissue engineering, a comparison of uniaxial and biaxial mechanical properties of the annulus fibrosus: a porcine model, does vibration influence the initiation of intervertebral disc herniation, novel lap test determines the mechanics of delamination between annular lamellae of the intervertebral disc, surfactant assisted incorporation of single-walled carbon nanotubes into a chitosan-polyvinylpyrrolidone polymer, an examination of the influence of strain rate on subfailure mechanical properties of the annulus fibrosus, biaxial mechanical testing of human sclera, effects of sclera stiffness on biomechanics of the optic nerve head in glaucoma, effects of sclera stiffness properties on optic nerve head biomechanics, fabrication of nanofiber reinforced protein structures for tissue engineering, strain uniformity in biaxial specimens is highly sensitive to attachment details, the influence of the tensile material properties of single annulus fibrosus lamellae and the interlamellar matrix strength on disc herniation and progression, functional arrays of human pluripotent stem cell-derived cardiac microtissues,a	cellscale	李先生
BioTester	an investigation of regional variations in the biaxial mechanical properties and stress relaxation behaviors of porcine atrioventricular heart valve leaflets, strain effects on collagen proteolysis in heart valve tissues, comparison of biomechanical properties and microstructure of trabeculae carneae, papillary muscles, and myocardium in the human heart, rate-dependency of the mechanical behavior of semilunar heart valves under biaxial deformation, an investigation of layer-specific tissue biomechanics of porcine atrioventricular valve anterior leaflets, the degradation and performance of electrospun supramolecular vascular scaffolds examined upon in vitro enzymatic exposure, mechanical damage characterization in human femoropopliteal arteries of different ages, cyclic strain affects macrophage cytokine secretion and extracellular matrix turnover in electrospun scaffolds, image-based analysis of uniaxial ring test for mechanical characterization of soft materials and biological tissues, mechanical properties of autologous pericardium change with fixation time: implications for valve reconstruction, tissue level mechanical properties and extracellular matrix investigation of the bovine jugular venous valve tissue, regional biaxial mechanical data of the mitral and tricuspid valve anterior leaflets, mechanics of the tricuspid valve-from clinical diagnosis/treatment, in-vivo and in-vitro investigations, to patient-specific biomechanical modeling., an investigation of the glycosaminoglycan contribution to biaxial mechanical behaviours of porcine atrioventricular heart valve leaflets, macrophage-driven biomaterial degradation depends on scaffold microarchitecture, the effect of axial torsion on the mechanical properties of the annulus fibrosus, integration of polarized spatial frequency domain imaging (psfdi) with a biaxial mechanical testing system for dynamic quantification of collagen architecture in soft collagenous tissues, an integrated opto-mechanical system for quantification of dynamic microstructure and mechanics of heart valve tissues, effects of longitudinal pre-stretch on the mechanics of human aorta before and after thoracic endovascular aortic repair (tevar) in trauma patients, human in vitro model of material-driven vascular regeneration reveals how cyclic stretch and shear stress differentially modulate inflammation and tissue formation, some effects of different constitutive laws on fsi simulation for the mitral valve, biomechanical restoration potential of pentagalloyl glucose after arterial extracellular matrix degeneration, an investigation of the effect of freezing storage on the biaxial mechanical properties of excised porcine tricuspid valve anterior leaflets, a detailed mechanical and microstructural analysis of the ovine tricuspid valve leaflets, the regional-dependent biaxial behavior of young and aged mouse skin: a detailed histomechanical characterization, residual strain analysis, and constitutive model, biaxial mechanical behavior of bovine saphenous venous valve leaflets, prevalence of calcification in human femoropopliteal arteries and its association with demographics, risk factors, and arterial stiffness, comparison of corneal biomechanics after myopic small-incision lenticule extraction compared to lasik: an ex vivo study, dehiscence of patch augmentation of a left-sided atrioventricular valve related to strenuous isometric exercise: case report and failure analysis, puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization, biomechanical evaluation of a personalized external aortic root support applied in the ross procedure, polydopamine as sizing on carbon fiber surfaces for enhancement of epoxy laminated composites, comparison of in vivo vs. ex situ obtained material properties of sheep common carotid artery, soy protein/cellulose nanofiber scaffolds mimicking skin extracellular matrix for enhanced wound healing, new findings confirm the viscoelastic behaviour of the inter-lamellar matrix of the disc annulus fibrosus in radial and circumferential directions of loading, 3d printed, controlled release, tritherapeutic tablet matrix for advanced anti-hiv-1 drug delivery, computational modeling guides tissue-engineered heart valve design for long-term in vivo performance in a translational sheep model, pressure-induced end-plate fracture in the porcine spine: is the annulus fibrosus susceptible to damage?, dual electrospun supramolecular polymer systems for selective cell migration, regional mechanical and biochemical properties of the porcine cortical meninges, new insights into the viscoelastic and failure mechanical properties of the elastic fiber network of the inter-lamellar matrix in the annulus fibrosus of the disc, initial scaffold thickness affects the emergence of a geometrical and mechanical equilibrium in engineered cardiovascular tissues, development of an improved parameter fitting method for planar biaxial testing using rakes, the biomechanics of the inter-lamellar matrix and the lamellae during progression to lumbar disc herniation: which is the weakest structure?, mechanically robust cryogels with injectability and bioprinting supportability for adipose tissue engineering, biomechanical characterization of human dura mater, 3d printed, pva–paa hydrogel loaded-polycaprolactone scaffold for the delivery of hydrophilic in-situ formed sodium indomethacin, a transverse isotropic constitutive model for the aortic valve tissue incorporating rate-dependency and fibre dispersion: application to biaxial deformation, decoupling the effect of shear stress and stretch on tissue growth and remodeling in a vascular graft, an investigation of the anisotropic mechanical properties and anatomical structure of porcine atrioventricular heart valves, biaxial mechanical data of porcine atrioventricular valve leaflets, biaxial mechanical characterization of atrioventricular heart valves, biaxial experimental and analytical characterization of a dielectric elastomer, biaxial mechanical properties of bovine jugular venous valve leaflet tissues, comparison of femoropopliteal artery stents under axial and radial compression, axial tension, bending, and torsion deformations, constitutive modeling of human femoropopliteal artery biaxial stiffening due to aging and diabetes, constitutive modeling of jugular vein-derived venous valve leaflet tissues, design and characterization of a hyperelastic tubular soft composite, in situ heart valve tissue engineering using a bioresorbable elastomeric implant – from material design to 12 months follow-up in sheep, jetvalve: rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement, limb flexion-induced twist and associated intramural stresses in the human femoropopliteal artery, mechanically robust electrospun hydrogel scaffolds crosslinked via supramolecular interactions, nondestructive mechanical characterization of developing biological tissues using inflation testing, on the influence of wall calcification and intraluminal thrombus on prediction of abdominal aortic aneurysm rupture, paraspinal muscle passive stiffness remodels in direct response to spine stiffness: a study using the ent1-deficient mouse, tensile behaviour of individual fibre bundles in the human lumbar anulus fibrosus, urinary bladder versus gastrointestinal tissue: a comparative study of their biomechanical properties for urinary tract reconstruction, a comparison between porcine, ovine, and bovine intervertebral disc anatomy and single lamella annulus fibrosis tensile properties, acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro, age-dependent changes in geometry, tissue composition and mechanical properties of fetal to adult cryopreserved human heart valves, are adipose-derived stem cells cultivated in human platelet lysate suitable for heart valve tissue engineering, biaxial quantification of deep layer transverse carpal ligament elastic properties by sex and region, biomechanical characterization of ascending aortic aneurysms, biomechanical properties and microstructure of heart chambers: a paired comparison study in an ovine model, characterization of three-dimensional anisotropic heart valve tissue mechanical properties using inverse finite element analysis, constitutive description of human femoropopliteal artery aging, deposition of a hydrophilic nanocomposite-based coating on a silicone hydrogel through a laser process to minimize uv exposure and bacterial contamination, improved geometry of decellularized tissue engineered heart valves to prevent leaflet retraction, inflation and bi-axial tensile testing of healthy porcine carotid arteries, modulation of collaen fiber orientation by strain-controlled enzymatic degradation, nanocomposited coatings produced by laser-assisted process to prevent silicone hydrogels from protein fouling and bacterial contamination, patient specific vascular benchtop models for development and validation of medical devices for minimally invasive procedures, peak stress in the annulus fibrosis under cyclic biaxial tensile loading, phototactic guidance of a tissue-engineered soft-robotic ray, planar biaxial testing of heart valve cusp replacement biomaterials: experiments, theory and material constants, planar biaxial testing of soft biological tissue using rakes: a critical analysis of protocol and fitting process, production of synthetic, para-aramid and biopolymer nanofibers by immersion rotary jet-spinning, quantification of coupled stiffness and fiber orientation remodeling in hypertensive rat right-ventricular myocardium using 3d ultrasound speckle tracking with biaxial testing, the aging disc: using an ovine model to examine age-related differences in the biomechanical properties of the intralamellar matrix of single lamellae, the choice of a constitutive formulation for modeling limb flexion-induced deformations and stresses in the human femoropopliteal arteries of different ages, the effect of local hydration environment on the mechanical properties and unloaded temporal changes of isolated porcine annular samples, adipose derived tissue engineered heart valve, biaxial stress relaxation of semilunar heart valve leaflets during simulated collagen catabolism: effects of collagenase concentration and equibiaxial strain state, building a better infarct: modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction, corneal collagen cross-linking combined with simulation of femtosecond laser-assisted refractive lens extraction: an ex vivo biomechanical effect evaluation, development of non-cell adhesive vascular grafts using supramolecular building blocks, high-irradiance cxl combined with myopic lasik: flap and residual stroma biomechanical properties studied ex-vivo, leaflet stress and strain distributions following incomplete transcatheter aortic valve expansion, methods for using 3-d ultrasound speckle tracking in biaxial mechanical testing of biological tissue samples, nanocomposite silicone hydrogels with a laser-assisted surface modification for inhibiting the growth of baterial biofilm, regional and depth variability of porcine meniscal mechanical properties through biaxial testing, superior tissue evolution in slow degrading scaffolds for valvular tissue engineering, the biomechanics of eyelid tarsus tissue, cardiac function of the naked mole-rat: echophysiological responses to working underground, directional biomechanical properties of porcine skin tissue, modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues, should a native depth-dependent distribution of human meniscus constitutive components be considered in fea-models of the knee joint?, strain-dependent modulation of macrophage polarization within scaffolds, structural and mechanical adaptations of right ventrical free wall myocardium to pressure overload, the biaxial biomechanical behavior of adominal aortic aneurysm tissue, the biaxial mechanical behaviour of abdominal aortic aneurysm intraluminal thrombus: classification of morphology and the determination of layer and region specific properties, the impact of long term freezing on the mechanical properties of porcine aortic tissue, vascular elastography: a validation study, a nanocomposite contact lens for the delivery of hydrophilic protein drugs, comparison of methods used to measure the thickness of soft tissues and their influence on the evaluation of tensile stress, corneal resistance to shear force after uva-riboflavin cross-linking, in vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells, mechanical analysis of ovine and pediatric pulmonary artery for heart valve stent design, mechanics of the pulmonary valve in the aortic position, reduction of stromal swelling pressure after uva-riboflavin cross-linking, a murine experimental model for the mechanical behavior of viable right-ventricular myocardium, an examination of the mechanical properties of the annulus fibrosus: the effect of vibration on the intra-lamellar matrix strength, application of simple biomechanical and biochemical tests to heart valve leaflets: implications for heart valve characterization and tissue engineering, biomechanical properties of the transverse carpal ligament under biaxial strain, multi-scale mechanical characterization of scaffolds for heart valve tissue engineering, a comparison of uniaxial and biaxial mechanical properties of the annulus fibrosus: a porcine model, does vibration influence the initiation of intervertebral disc herniation, novel lap test determines the mechanics of delamination between annular lamellae of the intervertebral disc, surfactant assisted incorporation of single-walled carbon nanotubes into a chitosan-polyvinylpyrrolidone polymer, an examination of the influence of strain rate on subfailure mechanical properties of the annulus fibrosus, biaxial mechanical testing of human sclera, effects of sclera stiffness on biomechanics of the optic nerve head in glaucoma, effects of sclera stiffness properties on optic nerve head biomechanics, fabrication of nanofiber reinforced protein structures for tissue engineering, strain uniformity in biaxial specimens is highly sensitive to attachment details, the influence of the tensile material properties of single annulus fibrosus lamellae and the interlamellar matrix strength on disc herniation and progression, functional arrays of human pluripotent stem cell-derived cardiac microtissues,a	cellscale	李先生
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	synthecon rccs灌流培养系统现货，3d低剪切力微重力灌流细胞培养系统，synthecon rccmax / rccmax-dual perfusion culture systems，synthecon rccs灌流培养系统（rccmax / rccmax-dual）是在标准rccs旋转培养基础上，集成连续灌流功能的升级系统。它在保留rccs低剪切力、模拟微重力等核心优势的同时，通过持续更新培养基，为细胞提供更接近体内的动态微环境。 image.png synthecon rccs灌注生物反应器系统，允许从外部培养基瓶持续向细胞培养室供液。培养基在系统中持续灌注，而细胞和支架的三维聚集体则通过多孔灌注芯保留在细胞培养室中。培养基还通过蠕动泵流经外部硅胶氧合器，以维持氧气水平。灌注培养系统的优势： • 在三维细胞培养过程中，无论是否停止容器旋转，均可更换、取样或调整培养基。 • 该系统可与支架一起使用，也可不使用支架来构建三维细胞模型。 • 培养基自动灌注到容器中，大限度地降低污染风险，并减少操作人员在培养过程中的干预。 • 适用于贴壁细胞类型。二、灌流培养的核心优势 1. 连续营养供给，减少人工干预灌流系统允许培养基连续灌注通过细胞培养室：自动换液：通过蠕动泵将新鲜培养基从外部储液瓶泵入培养室，同时排出废液减少污染风险：无需频繁开盖换液，显著降低操作带来的污染可能降低操作负担：适合长期培养实验，减少人工干预频率 2. 高效物质交换与代谢废物清除与静态培养和普通动态培养相比，灌流培养在物质传递方面具有显著优势： 3. 保留低剪切力环境灌流系统继承了rccs的核心优势：无气泡操作：通过硅胶膜进行气体交换，避免气泡破裂产生的剪切损伤细胞保留：培养室内的多孔灌流芯可保留细胞和3d聚集体，防止被冲出螺旋流特性：旋转与灌流结合形成螺旋poiseuille流，细胞在重力、科里奥利力、离心力等多重力场作用下沿周期性近圆轨迹运动 4. 支持组织工程大体积培养灌流系统配备更大体积的培养容器：三、技术亮点 1. 旋转与灌流双重力学环境灌流系统的核心创新在于旋转与轴向灌流的协同作用：螺旋poiseuille流：在管状组织（如食管）内部形成特的螺旋流动模式多力场耦合：细胞同时受到重力、阿基米德力、离心力、科里奥利力和曳力的作用参数优化窗口：流体动力学研究表明，转速<20 rpm、灌流速率<30 ml/min是组织工程应用的佳参数范围 2. 连续氧合保障硅胶膜氧合：气体通过培养容器背侧的硅胶膜扩散进入培养基，无需气泡外部氧合器：灌流系统中，培养基在循环过程中流经外部硅胶氧合器，确保持续供氧 3. 模块化设计，灵活扩展单站与双站可选：rccmax为单血管系统，rccmax-dual支持双血管立控制兼容性：灌流系统可搭配不同规格的培养容器，并兼容一次性或可重复使用耗材备件支持：rccmax-dual配备双倍备件套件，便于长期运行 4. nasa技术背景 rccs技术源自nasa旋转壁式生物反应器（rwv）专利：初为模拟太空微重力环境开发 synthecon于1990年获得nasa家专利并商业化灌流系统是在此基础上的功能扩展，专为组织工程优化四、灌流培养的应用场景 1. 组织工程与再生医学核心优势：灌流系统可有效实现脱细胞支架的再细胞化典型应用：食管组织工程：灌流系统用于食管脱细胞支架的细胞再植，实现细胞在支架内的均匀分布血管培养：支持定制化的管状器官培养气管重建：旋转-灌流双模式促进上皮细胞均匀沉积 2. 复杂类器官培养核心优势：持续营养供给支持类器官长期、稳定生长典型应用：视网膜类器官：nih眼科研究所研究证实，rccs灌流培养可加速和改善多能干细胞向视网膜类器官的分化与传统静态3d培养相比，分化更完、组织结构更接近体内 3. 脱细胞与再细胞化研究核心优势：灌流可增强脱细胞试剂的作用效果应用流程：通过灌流通道输送脱细胞试剂（如脱氧胆酸钠、dnase i）获得完整保留ecm结构的生物支架在相同灌流系统内进行再细胞化五、高分文献精选文献1：视网膜类器官分化研究（封面文章）标题：accelerated and improved differentiation of retinal organoids from pluripotent stem cells in rotating-wall vessel bioreactors 发表期刊：stem cell reports (cell press旗下，if: 5.9+) 发表时间：2018年1月研究机构：美国国立卫生研究院（nih）眼科研究所关键发现： rccs灌流培养显著加速视网膜类器官的形成分化得到的类器官组织结构更完整，更接近体内发育状态优于传统静态3d悬浮培养方法成果被选为isscr-stem cell reports期刊封面引用价值：nih官方研究，证明灌流系统在类器官分化效率方面的显著优势，是rccs灌流系统高影响力的文献之一。文献2：食管组织工程流体力学表征标题：fluid dynamics characterisation of a rotating bioreactor for tissue engineering 发表期刊：medical engineering & physics (if: 2.2) 发表时间：2022年6月研究机构：法国索邦大学、贡比涅技术大学、inserm 关键发现：系统建立了rccs灌流系统的流体动力学数学模型揭示旋转与灌流结合产生的螺旋poiseuille流特性确定佳操作参数：ω < 20 rpm，q < 30 ml/min 描述细胞颗粒在旋转参考系中的周期性近圆运动轨迹引用价值：为rccs灌流系统的参数优化和标准化提供理论依据，是该系统流体力学机理研究的权威文献。发表于同行评议的工程-生物医学期刊。		王经理
	synthecon rccs灌流培养系统现货，3d低剪切力微重力灌流细胞培养系统，synthecon rccmax / rccmax-dual perfusion culture systems，synthecon rccs灌流培养系统（rccmax / rccmax-dual）是在标准rccs旋转培养基础上，集成连续灌流功能的升级系统。它在保留rccs低剪切力、模拟微重力等核心优势的同时，通过持续更新培养基，为细胞提供更接近体内的动态微环境。 image.png synthecon rccs灌注生物反应器系统，允许从外部培养基瓶持续向细胞培养室供液。培养基在系统中持续灌注，而细胞和支架的三维聚集体则通过多孔灌注芯保留在细胞培养室中。培养基还通过蠕动泵流经外部硅胶氧合器，以维持氧气水平。灌注培养系统的优势： • 在三维细胞培养过程中，无论是否停止容器旋转，均可更换、取样或调整培养基。 • 该系统可与支架一起使用，也可不使用支架来构建三维细胞模型。 • 培养基自动灌注到容器中，大限度地降低污染风险，并减少操作人员在培养过程中的干预。 • 适用于贴壁细胞类型。二、灌流培养的核心优势 1. 连续营养供给，减少人工干预灌流系统允许培养基连续灌注通过细胞培养室：自动换液：通过蠕动泵将新鲜培养基从外部储液瓶泵入培养室，同时排出废液减少污染风险：无需频繁开盖换液，显著降低操作带来的污染可能降低操作负担：适合长期培养实验，减少人工干预频率 2. 高效物质交换与代谢废物清除与静态培养和普通动态培养相比，灌流培养在物质传递方面具有显著优势： 3. 保留低剪切力环境灌流系统继承了rccs的核心优势：无气泡操作：通过硅胶膜进行气体交换，避免气泡破裂产生的剪切损伤细胞保留：培养室内的多孔灌流芯可保留细胞和3d聚集体，防止被冲出螺旋流特性：旋转与灌流结合形成螺旋poiseuille流，细胞在重力、科里奥利力、离心力等多重力场作用下沿周期性近圆轨迹运动 4. 支持组织工程大体积培养灌流系统配备更大体积的培养容器：三、技术亮点 1. 旋转与灌流双重力学环境灌流系统的核心创新在于旋转与轴向灌流的协同作用：螺旋poiseuille流：在管状组织（如食管）内部形成特的螺旋流动模式多力场耦合：细胞同时受到重力、阿基米德力、离心力、科里奥利力和曳力的作用参数优化窗口：流体动力学研究表明，转速<20 rpm、灌流速率<30 ml/min是组织工程应用的佳参数范围 2. 连续氧合保障硅胶膜氧合：气体通过培养容器背侧的硅胶膜扩散进入培养基，无需气泡外部氧合器：灌流系统中，培养基在循环过程中流经外部硅胶氧合器，确保持续供氧 3. 模块化设计，灵活扩展单站与双站可选：rccmax为单血管系统，rccmax-dual支持双血管立控制兼容性：灌流系统可搭配不同规格的培养容器，并兼容一次性或可重复使用耗材备件支持：rccmax-dual配备双倍备件套件，便于长期运行 4. nasa技术背景 rccs技术源自nasa旋转壁式生物反应器（rwv）专利：初为模拟太空微重力环境开发 synthecon于1990年获得nasa家专利并商业化灌流系统是在此基础上的功能扩展，专为组织工程优化四、灌流培养的应用场景 1. 组织工程与再生医学核心优势：灌流系统可有效实现脱细胞支架的再细胞化典型应用：食管组织工程：灌流系统用于食管脱细胞支架的细胞再植，实现细胞在支架内的均匀分布血管培养：支持定制化的管状器官培养气管重建：旋转-灌流双模式促进上皮细胞均匀沉积 2. 复杂类器官培养核心优势：持续营养供给支持类器官长期、稳定生长典型应用：视网膜类器官：nih眼科研究所研究证实，rccs灌流培养可加速和改善多能干细胞向视网膜类器官的分化与传统静态3d培养相比，分化更完、组织结构更接近体内 3. 脱细胞与再细胞化研究核心优势：灌流可增强脱细胞试剂的作用效果应用流程：通过灌流通道输送脱细胞试剂（如脱氧胆酸钠、dnase i）获得完整保留ecm结构的生物支架在相同灌流系统内进行再细胞化五、高分文献精选文献1：视网膜类器官分化研究（封面文章）标题：accelerated and improved differentiation of retinal organoids from pluripotent stem cells in rotating-wall vessel bioreactors 发表期刊：stem cell reports (cell press旗下，if: 5.9+) 发表时间：2018年1月研究机构：美国国立卫生研究院（nih）眼科研究所关键发现： rccs灌流培养显著加速视网膜类器官的形成分化得到的类器官组织结构更完整，更接近体内发育状态优于传统静态3d悬浮培养方法成果被选为isscr-stem cell reports期刊封面引用价值：nih官方研究，证明灌流系统在类器官分化效率方面的显著优势，是rccs灌流系统高影响力的文献之一。文献2：食管组织工程流体力学表征标题：fluid dynamics characterisation of a rotating bioreactor for tissue engineering 发表期刊：medical engineering & physics (if: 2.2) 发表时间：2022年6月研究机构：法国索邦大学、贡比涅技术大学、inserm 关键发现：系统建立了rccs灌流系统的流体动力学数学模型揭示旋转与灌流结合产生的螺旋poiseuille流特性确定佳操作参数：ω < 20 rpm，q < 30 ml/min 描述细胞颗粒在旋转参考系中的周期性近圆运动轨迹引用价值：为rccs灌流系统的参数优化和标准化提供理论依据，是该系统流体力学机理研究的权威文献。发表于同行评议的工程-生物医学期刊。		王经理
	synthecon rccs灌流培养系统现货，3d低剪切力微重力灌流细胞培养系统，synthecon rccmax / rccmax-dual perfusion culture systems，synthecon rccs灌流培养系统（rccmax / rccmax-dual）是在标准rccs旋转培养基础上，集成连续灌流功能的升级系统。它在保留rccs低剪切力、模拟微重力等核心优势的同时，通过持续更新培养基，为细胞提供更接近体内的动态微环境。 image.png synthecon rccs灌注生物反应器系统，允许从外部培养基瓶持续向细胞培养室供液。培养基在系统中持续灌注，而细胞和支架的三维聚集体则通过多孔灌注芯保留在细胞培养室中。培养基还通过蠕动泵流经外部硅胶氧合器，以维持氧气水平。灌注培养系统的优势： • 在三维细胞培养过程中，无论是否停止容器旋转，均可更换、取样或调整培养基。 • 该系统可与支架一起使用，也可不使用支架来构建三维细胞模型。 • 培养基自动灌注到容器中，大限度地降低污染风险，并减少操作人员在培养过程中的干预。 • 适用于贴壁细胞类型。二、灌流培养的核心优势 1. 连续营养供给，减少人工干预灌流系统允许培养基连续灌注通过细胞培养室：自动换液：通过蠕动泵将新鲜培养基从外部储液瓶泵入培养室，同时排出废液减少污染风险：无需频繁开盖换液，显著降低操作带来的污染可能降低操作负担：适合长期培养实验，减少人工干预频率 2. 高效物质交换与代谢废物清除与静态培养和普通动态培养相比，灌流培养在物质传递方面具有显著优势： 3. 保留低剪切力环境灌流系统继承了rccs的核心优势：无气泡操作：通过硅胶膜进行气体交换，避免气泡破裂产生的剪切损伤细胞保留：培养室内的多孔灌流芯可保留细胞和3d聚集体，防止被冲出螺旋流特性：旋转与灌流结合形成螺旋poiseuille流，细胞在重力、科里奥利力、离心力等多重力场作用下沿周期性近圆轨迹运动 4. 支持组织工程大体积培养灌流系统配备更大体积的培养容器：三、技术亮点 1. 旋转与灌流双重力学环境灌流系统的核心创新在于旋转与轴向灌流的协同作用：螺旋poiseuille流：在管状组织（如食管）内部形成特的螺旋流动模式多力场耦合：细胞同时受到重力、阿基米德力、离心力、科里奥利力和曳力的作用参数优化窗口：流体动力学研究表明，转速<20 rpm、灌流速率<30 ml/min是组织工程应用的佳参数范围 2. 连续氧合保障硅胶膜氧合：气体通过培养容器背侧的硅胶膜扩散进入培养基，无需气泡外部氧合器：灌流系统中，培养基在循环过程中流经外部硅胶氧合器，确保持续供氧 3. 模块化设计，灵活扩展单站与双站可选：rccmax为单血管系统，rccmax-dual支持双血管立控制兼容性：灌流系统可搭配不同规格的培养容器，并兼容一次性或可重复使用耗材备件支持：rccmax-dual配备双倍备件套件，便于长期运行 4. nasa技术背景 rccs技术源自nasa旋转壁式生物反应器（rwv）专利：初为模拟太空微重力环境开发 synthecon于1990年获得nasa家专利并商业化灌流系统是在此基础上的功能扩展，专为组织工程优化四、灌流培养的应用场景 1. 组织工程与再生医学核心优势：灌流系统可有效实现脱细胞支架的再细胞化典型应用：食管组织工程：灌流系统用于食管脱细胞支架的细胞再植，实现细胞在支架内的均匀分布血管培养：支持定制化的管状器官培养气管重建：旋转-灌流双模式促进上皮细胞均匀沉积 2. 复杂类器官培养核心优势：持续营养供给支持类器官长期、稳定生长典型应用：视网膜类器官：nih眼科研究所研究证实，rccs灌流培养可加速和改善多能干细胞向视网膜类器官的分化与传统静态3d培养相比，分化更完、组织结构更接近体内 3. 脱细胞与再细胞化研究核心优势：灌流可增强脱细胞试剂的作用效果应用流程：通过灌流通道输送脱细胞试剂（如脱氧胆酸钠、dnase i）获得完整保留ecm结构的生物支架在相同灌流系统内进行再细胞化五、高分文献精选文献1：视网膜类器官分化研究（封面文章）标题：accelerated and improved differentiation of retinal organoids from pluripotent stem cells in rotating-wall vessel bioreactors 发表期刊：stem cell reports (cell press旗下，if: 5.9+) 发表时间：2018年1月研究机构：美国国立卫生研究院（nih）眼科研究所关键发现： rccs灌流培养显著加速视网膜类器官的形成分化得到的类器官组织结构更完整，更接近体内发育状态优于传统静态3d悬浮培养方法成果被选为isscr-stem cell reports期刊封面引用价值：nih官方研究，证明灌流系统在类器官分化效率方面的显著优势，是rccs灌流系统高影响力的文献之一。文献2：食管组织工程流体力学表征标题：fluid dynamics characterisation of a rotating bioreactor for tissue engineering 发表期刊：medical engineering & physics (if: 2.2) 发表时间：2022年6月研究机构：法国索邦大学、贡比涅技术大学、inserm 关键发现：系统建立了rccs灌流系统的流体动力学数学模型揭示旋转与灌流结合产生的螺旋poiseuille流特性确定佳操作参数：ω < 20 rpm，q < 30 ml/min 描述细胞颗粒在旋转参考系中的周期性近圆运动轨迹引用价值：为rccs灌流系统的参数优化和标准化提供理论依据，是该系统流体力学机理研究的权威文献。发表于同行评议的工程-生物医学期刊。		王经理
	spherefluidics微液滴单细胞包裹包覆与制备系统（picodroplet single cell encapsulation system,picodroplet single cell assay and isolation system）	spherefluidics
Cell Retrieval Kit	3d培养细胞回收试剂盒，cell-mate3d 培养物中回收细胞，cell retrieval kit	美国brti	李先生

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