AIM BIOTECH 3D细胞培养芯片(AIM Biotech Microfluidic 3D Cell Culture Chips)

型号:3D Cell Culture Chips
价格:请致电:010-67529703
品牌:aim biotech/flexcell

AIM BIOTECH 微流体三维凝胶培养芯片系统 现货



                             

flexcell Chipmate 3D细胞流体剪切应力加载培养分析是一种多用途的实验平台,已在多种生物学研究中得到了应用。

 1、Chipmate 3D细胞培养芯片采用三通道设计,中间为3D凝胶通道,两侧为培养基通道,通过负压吸引快速交换培养基。

 2、芯片透气性好,可有效进行气体交换 3采用标准载玻片尺寸(75 mm × 25 mm),兼容相差显微镜、荧光显微镜和激光共聚焦

显微镜 4可实现不同类型细胞的共培养

系统简介:

3D细胞培养芯片透气性好,而且用户可以通过选择不同的水凝胶,在间隔的3D2D空间进行不同类型细胞的培养。

同时可以通过对化学物浓度梯度和流体的调控很好地模拟符合用户特定需求的微环境。

1、Chipmate 3D细胞培养芯片采用三通道设计,中间为3D凝胶通道,两侧为培养基通道,通过负压吸引快速交换培养基。

2、芯片透气性好,可有效进行气体交换

3、采用标准载玻片尺寸(75 mm × 25 mm),兼容相差显微镜、荧光显微镜和激光共聚焦显微镜

4、可实现不同类型细胞的共培养

5、可在3D凝胶两侧产生化学梯度,也可控制3D凝胶中的间质流


芯片如下图:




6、配备Flexcell®公司的Collagel®和Thermacol®凝胶试剂盒

特性: 

1.多样化的聚合性凝胶填充

2.高效的气体交换

3.可控的流体及化学物浓度梯度

4.独特的共培养模型

· 1.     显微镜玻片尺寸 (75mm X 25mm)

2.     无菌 & 现成

3.     模块化设计,可利用AIM Luer Connectors开拓更多应用领域

4.     适用于386-孔板(AIM专有)

5.     底层所覆盖的是透光率高达92%的聚合物,因此该芯片可适用于相衬显微镜、荧光显微镜、2-photon & 共聚焦显微镜观察

6.     利用特殊的凹槽设计让培养基可以被快速地更换,即使使用真空抽吸器也不会有过度抽吸的风险


3-channel design : 3D gel region flanked by 2 media channels
  • Microscope slide format 75 mm X 25 mm.
  • Compatible with all polymerisable gels including collagen, fibrinogen, Matrigel, etc. and combinations thereof.
  • Gas permeable laminate for effective gas exchange.
  • Optically clear and compatible with phase contrast, fluorescence and confocal microscopy.
  • Enables monotypic or organotypic co-culture models.
  • Enables the control of interstitial flow across the 3D gel region.
  • Enables the control of chemical gradients across the 3D gel region.
  • Sterile and ready-to-use.
  • Designed for rapid media exchange through vacuum aspiration with no risk of over-aspiration.
  • Designed for modular expansion with AIM Connectors.
  • Fits into AIM Microtiter Plate Holders for easy handling and stacking.

Applications of AIM Biotech 3D Cell Culture Chips
  • Cell migration of both adherent and non-adherent cells and cell invasion
  • Angiogenesis and vasculogenesis
  • Metastatic cancer assays (spheroid dispersion and extravasation)
Key features of AIM microfluidic chips
  • Long working regions that are easily injectable with hydrogel, with low risk of leakage.
  • Gas permeable bottom laminate ensures accurate reflections of incubator conditions (normoxic or hypoxic).
  • Multicellular co-culture, with meaningful organization into models of biological systems.
  • Control over chemical gradients and flow across the gel region and/or within the media channels.

Microtiter Plate Holder 
with cover

 

Fits 3 AIM Chips for easy handling
Positions all chip inlets for compliance with the SBS/ANSI 384-well plate standard
Stackable to minimise incubator space usage
Includes built-in reservoirs and a cover for evaporation control

Luer Connectors

for modular expansion



Modular interface to connect: 
  • 1ml syringe barrels as media reservoirs or for gravity-driven flow
  • male luer tubing fittings to interface with tubing and syringe pumps for active flow control
  • future AIM accessories for new capabilities or usability features