产品名称 FasL, soluble Antibody from DIANOVA GmbH
产品货号 DIA-60
产品价格 现货询价,电话:010-67529703
产品规格 1 ml
产品品牌 DIANOVA GmbH
产品概述
产品详情
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Antigenic SpecificityFasL, soluble
Clone94
Host SpeciesMouse
Reactive Specieshuman, others not tested
IsotypeIgM
Formatpurified
Size1 ml
Concentrationn/a
ApplicationsIHC, Paraffin Sections, Frozen Sections, Immunofluorescence, Western Blot, Immunoprecipitation
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DescriptionFas ligand (FasL, CD 95L) is a type-II-membrane protein. Its receptor Fas (CD 95, Apo-1) is a cell-surface-type-I-membrane protein and a memberof the tumor necrosis factor (TNF) and nerve growth factor (NGF) receptor family. FasL induces apoptosis when interacting with its receptor Fas. FasL may exist aseither membrane bound (45 kD) or soluble forms (26 kD). The soluble protein can be released from cells upon cleavage by metalloproteinases. Binding of FasL to Fas triggers apoptotic cell death. FasL is predominantly expressed in activated T-lymphocytes and natural killer (NK) cells. FasL expression is reported in various tissues as thymus, liver, ovary, lung, heart and kidney. The Fas/FasL system has been shown to play a role in a number of human diseases, for example AIDS, hepatitis or cancer.
Immunogenhuman Fas Ligand sequence: aa 157- aa 343
Other NamesFas Ligand, FasL, CD95L, CD178
Gene, Accession #FASLK, 356
Catalog #DIA-60
Price
Order / More InfoFasL, soluble Antibody from DIANOVA GmbH
Product Specific Referencesn/a
产品资料