Exploring the neighborhood: adhesion-coupled cell mechanosensors
- PMID: 12150922
- DOI: 10.1016/s0092-8674(02)00831-0
Exploring the neighborhood: adhesion-coupled cell mechanosensors
Abstract
Here we discuss recent studies addressing adhesion-coupled mechanosensory processes and consider their molecular nature. Are cells using stretch-activated ion channels to explore the extracellular environment surrounding them, or do they use for that purpose the submembrane protein network that interconnects integrin receptors with the actin cytoskeleton?
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