产品详情 |
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Antigenic Specificity | AMPK alpha-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AMPK alpha-2 Polyclonal Antibody. AMPK2 alpha2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeo |
Immunogen | n/a |
Other Names | 5'-AMP-activated protein kinase, catalytic alpha-2 chain; AMPK alpha-2 chain |
Gene, Accession # | Entrez: 108079, 5563; Uniprot: P54646, Q8BRK8 |
Catalog # | PA5-14029 |
Price | |
Order / More Info | AMPK alpha-2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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