产品名称 AMPK alpha-1,2 Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-36045
产品价格 现货询价,电话:010-67529703
产品规格 100 µl
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityAMPK alpha-1,2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpurified
Size100 µl
Concentrationn/a
ApplicationsImmunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1000
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DescriptionAMPK alpha-1,2 Polyclonal Antibody. AMPK is a heterotrimeric complex comprising a catalytic alpha subunit and regulatory beta and gamma subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation. Activated AMPK can phosphorylate and regulate in vivo hydroxymethylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively. The human AMPK alpha1 and AMPK alpha2 genes encode 548 amino acid and
Immunogenn/a
Other Names5'-AMP-activated protein kinase catalytic subunit alpha-1, AMPK subunit alpha-1, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, au-protein kinase PRKAA1, PRKAA1, AMPK1, 5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK subunit alpha-2, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, PRKAA2, AMPK, AMPK2
Gene, Accession #Entrez: 105787, 108079, 5562, 5563, 65248, 78975; Uniprot: P54645, P54646, Q09137, Q13131, Q5EG47, Q8BRK8
Catalog #PA5-36045
Price
Order / More InfoAMPK alpha-1,2 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
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