产品详情 |
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Antigenic Specificity | AMPK alpha-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AMPK alpha-1 Polyclonal Antibody. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK. |
Immunogen | n/a |
Other Names | 5'-AMP-activated protein kinase, catalytic alpha-1 chain; AMPK alpha-1 chain |
Gene, Accession # | Entrez: 105787, 5562; Uniprot: Q13131, Q5EG47 |
Catalog # | PA5-14026 |
Price | |
Order / More Info | AMPK alpha-1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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