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| Product Name | Prostaglandin I2 (sodium salt) |
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| Description | PGI2 is an unstable COX metabolite detected first in vascular endothelial cells.{502,443,933} It elevates platelet cAMP and is a potent vasodilator and inhibitor of human platelet aggregation with an IC50 value of 5 nM.{4375} PGI2 is stable in basic buffers (pH=8), but it is rapidly hydrolyzed to 6-keto PGF1α in neutral or acidic solutions. The half-life is short both in vivo and in vitro, ranging from 30 seconds to a few minutes. PGI2 is administered by continuous infusion in humans for the treatment of idiopathic pulmonary hypertension.{5466} |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Epoprostenol|PGI2|Prostacyclin |
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| Gene, Accession, CAS # | CAS: 61849-14-7 |
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| Catalog # | 18220-1 |
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| Order / More Info | Prostaglandin I2 (sodium salt) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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