| 产品详情 |
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| Antigenic Specificity | CD58 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HI58a reacts with a membrane glycoprotein of 55-70kDa which occurs either as a transmembrane moiety with a cytoplasmic domain or resident in the membrane. CD58 is a cell adhesion molecule of the Super Ig family, and facilitates antigen recognition via CD2. The antigen is present on erythrocytes, platelets, monocytes, bone marrow cells, a lymphocyte subset and epithelial and endothelial cells. Recognizes the human CD58 cell surface antigen. CD58 is a cell adhesion molecule, which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes. It is a member of the immunoglobulin superfamily of molecules. CD58 has a wide tissue distribution, being present on erythrocytes, platelets, monocytes, a subset of lymphocytes, bone marrow cells, epithelium, and endothelial cells. There are approximately 5,000 CD58 molecules on each erythrocyte. There is reduced expression of CD58 on haemopoietic cells in individuals with paroxysmal nocturnal haemoglobinuria. |
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| Immunogen | CD58 transfected CHO cell line. |
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| Other Names | ag3; LFA3; LFA-3; Surface glycoprotein LFA-3; CD58; Lymphocyte function-associated antigen 3; Surface glycoprotein LFA-4; Surface glycoprotein LFA-5; Surface glycoprotein LFA-6; MAb to CD58; CD antigen CD58 |
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| Gene, Accession # | Gene ID: 965, SwissProt: P19256 |
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| Catalog # | abx200386 |
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| Price | |
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| Order / More Info | CD58 Antibody from ABBEXA |
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| Product Specific References | n/a |
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