| 产品详情 |
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| Antigenic Specificity | CD57 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgM |
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| Format | fluorescein (FITC) conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This antibody reacts with a carbohydrate antigen present on a subset of peripheral blood mononuclear cells involved in the Natural Killer activity, which is not MHC restricted. The antigen is not present on B cells, monocytes, red blood cells or platelets but is expressed on cells in neuroectodermal tissue. It reacts with 20% of normal human peripheral blood mononuclear cells. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants). |
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| Immunogen | Human neuroblastoma cells. |
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| Other Names | CD57; HNK-1; NK-1; Leu-7; MAB TO CD57; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; Beta-1 3-glucuronyltransferase 1; Glucuronosyltransferase-P; GlcAT-P; UDP-GlcUA:glycoprotein beta-1 3-glucuronyltransferase; GlcUAT-P; B3GAT1; GLCATP; Beta-1.3-glucuronyltransferase 1; Glucuronosyltransferase P; UDP-GlcUA:glycoprotein beta-1.3-glucuronyltransferase |
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| Gene, Accession # | Gene ID: 27087, SwissProt: Q96E93 |
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| Catalog # | abx200385 |
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| Price | |
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| Order / More Info | CD57 Antibody from ABBEXA |
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| Product Specific References | n/a |
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