| 产品详情 |
| Edit |   |
| Antigenic Specificity | CD57 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgM |
| Format | affinity purified |
| Size | 100 µg |
| Concentration | n/a |
| Applications | FCM. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody reacts with a carbohydrate antigen present on a subset of peripheral blood mononuclear cells involved in the Natural Killer activity, which is not MHC restricted. The antigen is not present on B cells, monocytes, red blood cells or platelets but is expressed on cells in neuroectodermal tissue. It reacts with 20% of normal human peripheral blood mononuclear cells. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants). |
| Immunogen | Human neuroblastoma cells. |
| Other Names | CD57; HNK-1; NK-1; Leu-7; MAB TO CD57; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; Beta-1 3-glucuronyltransferase 1; Glucuronosyltransferase-P; GlcAT-P; UDP-GlcUA:glycoprotein beta-1 3-glucuronyltransferase; GlcUAT-P; B3GAT1; GLCATP; Beta-1.3-glucuronyltransferase 1; Glucuronosyltransferase P; UDP-GlcUA:glycoprotein beta-1.3-glucuronyltransferase |
| Gene, Accession # | Gene ID: 27087, SwissProt: Q96E93 |
| Catalog # | abx200384 |
| Price | |
| Order / More Info | CD57 Antibody from ABBEXA |
| Product Specific References | n/a |
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