产品详情 |
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Antigenic Specificity | Nogo Receptor |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: 1-3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nogo Receptor Polyclonal Antibody. NgBR, also known as Nogo-B receptor, is a 293 amino acid rich member of the UPP synthetase family. Though the extact fundtion of NgBR is still not clear, reports suggest that this membrane protein acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. It has similarity with UPP synthetase proteins which suggests that it may act as a scaffold for the binding of isoprenyl lipids and/or prenylated proteins but has no lipid transferase activity. NgBR colocalizes with Nogo-B during VEGF and wound healing angiogenesis and is thus able to regulate vascular remodeling and angiogenesis. Nogo-B and NgBR mediate chemotaxis in HUVECs and induced tube formation in three-dimensi |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 113912, 65078, 65079; Uniprot: Q99M75, Q99PI8, Q9BZR6 |
Catalog # | PA1-41202 |
Price | |
Order / More Info | Nogo Receptor Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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