| 产品详情 |
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| Antigenic Specificity | Nogo Receptor |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Nogo Receptor Polyclonal Antibody. CNS white matter is selectively inhibitory for axonal outgrowth. Nogo is an oligodendrocyte-specific member of the reticulon family and is a component of CNS white matter that prevents axonal regeneration in the adult CNS. Nogo is expressed by oligodendrocytes and associates primarily with the endoplasmic reticulum. The extracellular domain of Nogo, designated Nogo-66 inhibits axonal extension, but does not alter non-neuronal cell morphology. Expression of a brain-specific, leucine-rich-repeat protein with high affinity for Nogo-66, the Nogo-66 receptor (Nogo-R), is sufficient to impart Nogo-66 axonal inhibition to unresponsive neurons. Disruption of the interaction between Nogo-66 and Nogo-R potentially p |
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| Immunogen | n/a |
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| Other Names | Reticulon-4 receptor; Nogo receptor; NgR; Nogo-66 receptor; RTN4R; NOGOR; UNQ330/PRO526 |
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| Gene, Accession # | Entrez: 113912, 65078, 65079; Uniprot: Q99M75, Q99PI8, Q9BZR6 |
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| Catalog # | PA5-77029 |
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| Price | |
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| Order / More Info | Nogo Receptor Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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