| 产品详情 |
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| Antigenic Specificity | RUNX1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RUNX1 Antibody is a Rabbit Polyclonal antibody against RUNX1. AML1 (also known as Runx1, CBFA2, and PEBP2αB) is a member of the core binding factor (CBF) family of transcription factorsIt is required for normal development of all hematopoietic lineagesAML1 forms a heterodimeric DNA binding complex with its partner protein CBFβ and regulates the expression of cellular genes by binding to promoter and enhancer elementsAML1 is commonly translocated in hematopoietic cancers: chromosomal translocations include t(8;21) AML1-ETO, t(12;21) TEL-AML, and t(8;21) AML-M2Phosphorylation of AML1 on several potential serine and threonine sites, including Ser249, is thought to occur in an Erk-dependent manner. |
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| Immunogen | A synthetic peptide of human RUNX1. |
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| Other Names | AML1; AML1-EVI-1; AMLCR1; CBFA2; EVI-1; PEBP2Ab; RUNX1; Runt-related transcription factor 1; Acute myeloid leukemia 1 protein; Core-binding factor subunit alpha-2; CBF-alpha-2; Oncogene AML-1; Polyomavirus enhancer-binding protein 2 alpha B subunit; PEA2-alpha B; PEBP2-alpha B; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor alpha B subunit |
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| Gene, Accession # | RUNX1, Gene ID: 861, SwissProt: Q01196 |
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| Catalog # | abx117189 |
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| Price | |
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| Order / More Info | RUNX1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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