产品详情 |
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Antigenic Specificity | RCAN2 |
Clone | 1A9 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: 1-5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RCAN2 Monoclonal Antibody (1A9). Regulator of calcineurin 2 (RCAN2), also known as ZAKI4 and DSCR1L1, is expressed as two isoforms differing at their N-terminus. The longer of the two (isoform 1) is expressed exclusively in the brain, while isoform 2 is ubiquitously expressed, with highest expression in brain, heart, and muscle. Both isoforms bind to the catalytic subunit of calcineurin, a Ca++-dependent protein phosphatase involved in several neuronal functions, though their C-terminal region and inhibit calcineurin's activity. Unlike isoform 1 of RCAN2, the expression of the second isoform is not induced by the thyroid hormone T3. RCAN2 is a member of a family of three endogenous calcineurin regulators that are located near the minimal su |
Immunogen | n/a |
Other Names | Csp2, Dscr1l1, MCIP2, ZAKI-4; Down syndrome critical region gene 1-like 1; calcineurin inhibitory protein ZAKI-4; calcipressin-2; down syndrome candidate region 1-like protein 1; myocyte-enriched calcineurin interactin protein 2; myocyte-enriched calcineurin-interacting protein 2 |
Gene, Accession # | Entrez: 10231; Uniprot: Q14206 |
Catalog # | MA5-24549 |
Price | |
Order / More Info | RCAN2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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