| 产品详情 |
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| Product Name | Tosedostat |
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| Description | An aminopeptidase inhibitor (IC50s = 100, 150, and 220 nM for LAP, PUSA, and aminopeptidase N, respectively); inhibits proliferation of human leukemia cell lines in vitro irrespective of p53, PTEN, or K-RAS mutational status (IC50s = 10-770 nM); induces up-regulation of genes in amino acid transport and metabolic pathways and inhibits phosphorylation of mTOR substrates in HL-60 cells; reduces total tumor burden and the number of spontaneous metastases in a mouse MDA-MB-435 xenograft model when administered at a dose of 100 mg/kg |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CHR-2797 |
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| Gene, Accession, CAS # | CAS: 238750-77-1 |
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| Catalog # | 23395-1 |
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| Price | |
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| Order / More Info | Tosedostat from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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