| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | LRP1 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot: 1:500-1:3000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | LRP1 Polyclonal Antibody. LRP1 encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease |
|---|
| Immunogen | n/a |
|---|
| Other Names | LRP1A, A2MR, LRP, TGFBR5, CD91, APR, APOER, IGFBP3R, low density lipoprotein receptor-related protein 1, LRP1 |
|---|
| Gene, Accession # | Entrez: 4035; Uniprot: Q07954 |
|---|
| Catalog # | PA5-78044 |
|---|
| Price | |
|---|
| Order / More Info | LRP1 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|