| 产品详情 |
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| Antigenic Specificity | LRP1 |
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| Clone | A2MR-beta-1 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Flow Cytometry: Assay Dependent, Immunohistochemistry (Frozen): 1:1000, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LRP1 Monoclonal Antibody (A2MR-beta-1). The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. |
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| Immunogen | n/a |
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| Other Names | A2MR, APOER, APR, CD91, FLJ16451, IGFBP3R, LRP, MGC88725, TGFBR5 |
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| Gene, Accession # | Entrez: 16971, 299858, 4035; Uniprot: Q07954, Q91ZX7 |
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| Catalog # | 37-7600 |
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| Price | |
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| Order / More Info | LRP1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 24126057, 25736295, 26846992 |
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