| 产品详情 |
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| Antigenic Specificity | NOD1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC, IF/ICC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. This NOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 923-951 amino acids from the C-terminal region of human NOD1. |
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| Immunogen | Human NOD1. |
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| Other Names | NOD1; CARD4; CLR7.1; NLRC1; Nucleotide-binding oligomerization domain-containing protein 1; Caspase recruitment domain-containing protein 4; Nucleotide Binding Oligomerization Domain Containing Protein 1; Caspase Recruitment Domain Family,Member 4; Nucleotide-Binding Oligomerization Domain,Leucine Rich Repeat And CARD Domain Containing 1 |
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| Gene, Accession # | SwissProt: Q9Y239 |
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| Catalog # | abx026454 |
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| Price | |
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| Order / More Info | NOD1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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