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Antigenic Specificity | CX3CL1 (Fractalkine) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 50 µg |
Concentration | n/a |
Applications | Immunohistochemistry (Frozen): 1:100-1:500, Immunoprecipitation: 1:300-1:800, Western Blot: 1:1000-1:5000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CX3CL1 (Fractalkine) Polyclonal Antibody, eBioscience™. Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope f |
Immunogen | n/a |
Other Names | ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin |
Gene, Accession # | Entrez: 20312, 6376, 89808; Uniprot: O35188, O55145, P78423 |
Catalog # | 14-7986-81 |
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Order / More Info | CX3CL1 (Fractalkine) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 15880821, 18640154, 21494375, 21718473, 27549131 |
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