| 产品详情 |
| Edit |   |
| Antigenic Specificity | LDLR |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl |
| Concentration | n/a |
| Applications | WB, FCM. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. This LDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the Central region of human LDLR. |
| Immunogen | Human LDLR. |
| Other Names | FH; FHC; LDLCQ2; LDLR; LDL receptor; Low-density lipoprotein receptor |
| Gene, Accession # | LDLR, SwissProt: P01130 |
| Catalog # | abx034176 |
| Price | |
| Order / More Info | LDLR Antibody from ABBEXA |
| Product Specific References | n/a |
| 产品资料 |
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