| 产品详情 |
| Edit |   |
|---|
| Product Name | Gedunin |
|---|
| Description | A natural inhibitor of p23 chaperone function; inhibits Hsp90 expression in vitro in NTERA-2 cells at 5 µg/ml; binds to and blocks p23 to induce apoptosis in HeLa-PRB cells (20 µM); inhibits breast cancer cell proliferation in vitro (IC50s = 8.84 and 3.22 µM in MCF-7 and SKBr-3 cells, respectively); inhibits PANC-1 pancreatic cancer cell growth in vitro (IC50 = 25 µM); has anti-inflammatory effects in mouse models of articular inflammation when used at doses of 0.05-0.5 mg/kg and allergic inflammation when used at a dose of 0.5 mg/kg; targets LPS binding and TLR4 signaling in macrophages when used at a concentration of 10 µM |
|---|
| Size | 500 µg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | NSC 113497 |
|---|
| Gene, Accession, CAS # | CAS: 2753-30-2 |
|---|
| Catalog # | 17328-500 |
|---|
| Price | |
|---|
| Order / More Info | Gedunin from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|