产品详情 |
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Antigenic Specificity | B3GNT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | B3GNT1 Polyclonal Antibody. Beta-1,4-glucuronyltransferase involved in O- mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE, during synthesis of phosphorylated O- mannosyl glycan (PubMed:25279699, PubMed:25279697). Phosphorylated O-mannosyl glycan is a carbohydrate is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:25279699, PubMed:25279697). Required for axon guidance; via its function in O-mannosylation of alpha- dystroglycan (DAG1). |
Immunogen | n/a |
Other Names | Beta-1, 4-glucuronyltransferase 1, 241-, I-beta-1, 3-N-acetylglucosaminyltransferase, iGnT, N-acetyllactosaminide beta-1, 3-N-acetylglucosaminyltransferase, Poly-N-acetyllactosamine extension enzyme, UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 1, B3GNT1 (HGNC:15685) |
Gene, Accession # | Entrez: 11041; Uniprot: O43505 |
Catalog # | PA5-48528 |
Price | |
Order / More Info | B3GNT1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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