| 产品详情 |
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| Antigenic Specificity | RNF144B |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se. This RNF144B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the Central region of human RNF144B. |
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| Immunogen | Human RNF144B. |
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| Other Names | bA528A10.3; E3 ubiquitin-protein ligase RNF144B; IBR domain containing 2; IBR domain-containing protein 2; IBRDC2; KIAA0161; MGC71786; p53-inducible RING finger protein; P53RFP; R144B; ring finger 144B; RING finger protein 144B; RNF144B |
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| Gene, Accession # | RNF144B, SwissProt: Q7Z419 |
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| Catalog # | abx030426 |
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| Price | |
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| Order / More Info | RNF144B Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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