产品详情 |
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Product Name | NIBR0213 |
Description | A potent and selective S1P1 antagonist (IC50s = 2.5 and 2.0 nM for hS1P1 Ca2+ mobilization and in a GTPγS assay); inactive at S1P2, S1P3, and S1P4 receptors (IC50s = >20, >10, and >10 µM, respectively in a Ca2+ mobilization assay); reduces EAE disease severity in mice up to 26 days; induces pulmonary damage in rats when administered chronically |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NIBR-0213 S1P-1 2 3 4 PBL |
Gene, Accession, CAS # | CAS: 1233332-14-3 |
Catalog # | 21513-25 |
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Order / More Info | NIBR0213 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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