| 产品详情 |
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| Antigenic Specificity | Caspase 8 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Immunohistochemistry (Paraffin): 1:1000, Immunoprecipitation: 1:2000, Western Blot: 1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase 8 Polyclonal Antibody. Caspase 8 (CASP8) is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases play a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a pro-domain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. Caspase 8 is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of Caspase 8 suggests that it may interact with Fas-interacting protein FADD. Caspase 8 was detect |
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| Immunogen | n/a |
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| Other Names | Caspase-8, FLICE, MACH, Mch5 |
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| Gene, Accession # | Entrez: 12370, 64044, 841; Uniprot: O89110, Q14790, Q9JHX4 |
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| Catalog # | PA1-29159 |
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| Price | |
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| Order / More Info | Caspase 8 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 26998763, 27798717 |
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