| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Caspase 8 |
|---|
| Clone | FLICE 4-1-20 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1, kappa |
|---|
| Format | purified |
|---|
| Size | 200 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot: 1:1000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Caspase 8 Monoclonal Antibody (FLICE 4-1-20). Caspase 8 (CASP8) is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases play a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a pro-domain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. Caspase 8 is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of Caspase 8 suggests that it may interact with Fas-interacting protein FADD. Caspa |
|---|
| Immunogen | n/a |
|---|
| Other Names | ALPS2B, CAP4, Casp-8, FLICE, FLJ17672, MACH, MCH5, MGC78473 |
|---|
| Gene, Accession # | Entrez: 841; Uniprot: Q14790 |
|---|
| Catalog # | MA1-16841 |
|---|
| Price | |
|---|
| Order / More Info | Caspase 8 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|