| 产品详情 |
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| Antigenic Specificity | Septin 2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-10 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Septin 2 Polyclonal Antibody. Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri. |
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| Immunogen | n/a |
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| Other Names | SEPT2; septin 2; DIFF6; KIAA0158; NEDD5; Pnutl3; hNedd5; neural precursor cell expressed, developmentally down-regulated 5 |
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| Gene, Accession # | Entrez: 18000, 4735; Uniprot: P42208, Q15019 |
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| Catalog # | A304-211A |
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| Price | |
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| Order / More Info | Septin 2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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