| 产品详情 |
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| Antigenic Specificity | CD82 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 2.5 µg/mL, Western Blot: 0.5-1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD82 Polyclonal Antibody. KAI1 was initially identified from a T-cell activation study as a four-transmembrane protein that plays an accessory role in T-cell activation, and was later determined to act as a cancer metastasis suppressor gene. This protein is ubiquitously expressed at moderate to high levels in most tissues, but its expression is downregulated during tumor progression. The loss of KAI1 and p53 is associated with poor survival for prostate and other cancer patients. Recently, KAI1 was found to interact with DARC, the Duffy antigen for chemokines using a yeast two hybrid screen. It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells, transmitti |
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| Immunogen | n/a |
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| Other Names | 4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27, C33 antigen, CD82 antigen, inducible membrane protein R2 |
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| Gene, Accession # | Entrez: 12521, 3732, 83628; Uniprot: O70352, P27701, P40237 |
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| Catalog # | PA5-20356 |
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| Price | |
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| Order / More Info | CD82 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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