产品详情 |
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Antigenic Specificity | CD62L |
Clone | MEL-14 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | PE-Cy5 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE/Cy5 anti-mouse CD62L. CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte rolling on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1. |
Immunogen | C3H/eb mouse B lymphoma 38C-13 |
Other Names | L-selectin, LECAM-1, Ly-22, LAM-1, MEL-14 |
Gene, Accession # | Gene ID: 20343 |
Catalog # | 104410 |
Price | |
Order / More Info | CD62L Antibody from BIOLEGEND |
Product Specific References | PubMed: 16431965,17620363,17702899,18818390,19681828 |
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