产品详情 |
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Product Name | Roridin E |
Description | A macrocyclic trichothecene mycotoxin that has been found in M. verrucaria; inhibits FGFR3, IGF-1R, PDGFRβ, and TrkB (IC50s = 0.4, 0.4, 1.4, and 1 µM, respectively); induces cytotoxicity in multiple breast cancer cell lines (IC50s = 0.02-0.05 nM); inhibits proliferation in a panel of additional cancer cell lines (IC50s = 50s = 1.74-7.68 nM); inhibits the growth of P. falciparum (EC50 = 0.15 ng/ml); induces phytotoxicity in duckweed and kudzu; toxic to mice (LD50 = 10 mg/kg, i.p.); also produced by the plant B. coridifiola, which is associated with livestock poisoning in South America |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 16891-85-3 |
Catalog # | 26955-1 |
Price | |
Order / More Info | Roridin E from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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