| 产品详情 |
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| Antigenic Specificity | CCDC88A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-10 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CCDC88A Polyclonal Antibody. Girdin is a Galpha-interacting protein that can enhance the activation of the protein kinase Akt, remodel the actin cytoskeleton, and is thought to be involved in the regulation of cell migration and cancer metastasis. It has recently been shown that Girdin interacts with Disrupted-in-Schizophrenia 1 (DISC1), a susceptibility gene for major psychiatric disorders. DISC1 is thought to be involved in the migration, positioning and differentiation of dentate granule cells (DGCs) during development; depletion of Girdin or blocking the Girdin-DISC1 interaction results in defects in axonal sprouting in the CA3 region of the hippocampus and overextended migration of mispositioning of DGCs, suggesting the Girdin plays a |
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| Immunogen | n/a |
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| Other Names | APE, GIRDIN, GIV, GRDN, HkRP1, KIAA1212; AKT-phosphorylation enhancer; Galpha-interacting vesicle-associated protein; G{alpha}-interacting vesicle-associated protein; Hook-related protein 1; akt phosphorylation enhancer; coiled-coil domain-containing protein 88A; g alpha-interacting vesicle-associated protein; girders of actin filament; girdin |
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| Gene, Accession # | Entrez: 55704; Uniprot: Q3V6T2 |
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| Catalog # | A303-102A |
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| Price | |
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| Order / More Info | CCDC88A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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