| 产品详情 |
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| Antigenic Specificity | mutated Calreticulin (CALR) |
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| Clone | CAL2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 250 µl |
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| Concentration | n/a |
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| Applications | IHC, Paraffin Sections (FFPE) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CAL2 labels the megakaryocytes in myeloproliferative neoplasms (essential thrombocythaemia (ET) and primary myelofibrosis (PMF)) with CALR mutation and enables to distinguish ET and PMF with CALR mutation from polycythemia vera (PV), from CALR mutation negative ET and PMF and from reactive bone marrow. |
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| Immunogen | C-neoterminus of mutated CALR |
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| Other Names | Sicca Syndrome Antigen A, Endoplasmic Reticulum Resident Protein 60, Calregulin, ERp60, CRP55, HACBP, Grp60, Epididymis Secretory Sperm Binding Protein Li 99n, Autoantigen Ro, HEL-S-99n, CC1qR, CRTC, SSA, CRT, RO |
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| Gene, Accession # | CALR_HUMAN, P27797 |
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| Catalog # | DIA-CAL-250 |
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| Order / More Info | mutated Calreticulin (CALR) Antibody from DIANOVA GmbH |
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| Product Specific References | A new monoclonal antibody (CAL2) detects CALRETICULIN mutations in formalin-fixed and paraffin-embedded bone marrow biopsies.Stein H, Bob R, Durkop H, Erck C, Kampfe D, Kvasnicka HM, Martens H, Roth A, Streubel A., Leukemia. 2015 Jul 23. doi: 10.1038/leu.2015.192. |
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