| 产品详情 |
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| Antigenic Specificity | alpha Adaptin |
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| Clone | AP6 |
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| Host Species | Mouse |
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| Reactive Species | bovine, hamster, human, mouse, nonhuman primate, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1 µg / 10^6 cells, Immunocytochemistry: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL, Immunohistochemistry (PFA fixed): Assay Dependent, Immunoprecipitation: Assay dependent, Inhibition Assays: Assay Dependent, Western Blot: 1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | alpha Adaptin Monoclonal Antibody (AP6). Clathrin-mediated endocytosis is the pathway by which many receptors for nutrients and hormones are internalized to be recycled or down-regulated. During formation of clathrin coated membranes, clathrin co-assembles with heterotetrameric molecules known as assembly polypeptides (APs) or adaptors which form a layer of protein coat between the clathrin lattice and the membrane. There are two characterized adaptors AP1 and AP2. AP1 is associated with clathrin coated vesicles at the trans-Golgi network and AP2 is associated with the endocytic clathrin coated vesicles at the plasma membrane and has been shown to specifically interact with Shc and EGF receptor. AP2 is composed of four subunits, two separat |
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| Immunogen | n/a |
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| Other Names | AP2 |
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| Gene, Accession # | Entrez: 100772481, 11771, 160, 308578, 784636; Uniprot: O95782, P17426 |
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| Catalog # | MA1-064 |
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| Price | |
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| Order / More Info | alpha Adaptin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11331580, 12198492, 14742709, 15331762, 15557176, 15689492, 15923653, 15987739, 1607381, 16412388, 16537571, 16801533, 17293591, 17555536, 19509056, 19706427, 20028792, 22216966, 22323287, 22399289, 24046449, 24076656, 25517094, 26589353, 26779610, 27551500, 28360834 |
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