| Edit |   |
|---|
| Antigenic Specificity | Nanog (pS285) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | peptide affinity purified |
|---|
| Size | 80 µl, 400 µl |
|---|
| Concentration | n/a |
|---|
| Applications | DB. RUO |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | NANOG is a Ttranscription regulator involved in inner cell mass and embryonic stem (ES) cels proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation. This Nanog Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S285 of human Nanog. |
|---|
| Immunogen | Human Nanog (phospho-Ser285). |
|---|
| Other Names | Homeobox protein NANOG; NANOG; Homeobox transcription factor Nanog; hNanog; ECAT4; ENK; ES cell-associated protein 4; Early embryo specific expression NK-type homeobox protein; Nanog homeobox; 2410002E02Rik, ENK, ecat4; early embryo specific expression NK family; HGNC:20857; homeobox transcription factor Nanog-delta 48 |
|---|
| Gene, Accession # | SwissProt: Q9H9S0 |
|---|
| Catalog # | abx032059 |
|---|
| Price | |
|---|
| Order / More Info | Nanog (pS285) Antibody from ABBEXA |
|---|
| Product Specific References | n/a |
|---|