产品详情 |
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Antigenic Specificity | N-cadherin |
Clone | 13A9 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Immunoprecipitation: 2 µg, Western Blot: 1:200-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | N-cadherin Monoclonal Antibody (13A9). N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five e |
Immunogen | n/a |
Other Names | Cadherin-2, CDw325, CD325 Neural cadherin, Calcium-Dependent Adhesion Protein |
Gene, Accession # | Entrez: 1000, 12558; Uniprot: P15116, P19022 |
Catalog # | MA1-159 |
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Order / More Info | N-cadherin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 10506713, 15838877, 29042773 |
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