| 产品详情 |
| Edit |   |
| Antigenic Specificity | EGLN1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, monkey |
| Isotype | n/a |
| Format | affinity purified |
| Size | 50 µl, 100 µl, 200 µl |
| Concentration | > 1 mg/ml |
| Applications | WB. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | EGLN1 Antibody is a Rabbit Polyclonal antibody against EGLN1. The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). |
| Immunogen | Recombinant protein of human EGLN1. |
| Other Names | C1orf12; Egl nine homolog 1; Hypoxia-inducible factor prolyl hydroxylase 2; HIF-PH2; HIF-prolyl hydroxylase 2; HPH-2; Prolyl hydroxylase domain-containing protein 2; PHD2; SM-20; EGLN1; DKFZp761F179; ECYT3; HIFPH2; HPH2; SM20; ZMYND6; Elongation factor Tu GTP-binding domain-containing protein 2; SNU114 homolog; hSNU114; U5 snRNP-specific protein; 116 kDa; U5-116 kDa; EFTUD2; KIAA0031; SNRP116 |
| Gene, Accession # | EGLN1, Gene ID: 54583, SwissProt: Q9GZT9 |
| Catalog # | abx001065 |
| Price | |
| Order / More Info | EGLN1 Antibody from ABBEXA |
| Product Specific References | n/a |
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