| 产品详情 |
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| Antigenic Specificity | EGLN1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). This EGLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-425 amino acids from the C-terminal region of human EGLN1. |
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| Immunogen | Human EGLN1. |
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| Other Names | C1orf12; Egl nine homolog 1; Hypoxia-inducible factor prolyl hydroxylase 2; HIF-PH2; HIF-prolyl hydroxylase 2; HPH-2; Prolyl hydroxylase domain-containing protein 2; PHD2; SM-20; EGLN1; DKFZp761F179; ECYT3; HIFPH2; HPH2; SM20; ZMYND6; Elongation factor Tu GTP-binding domain-containing protein 2; SNU114 homolog; hSNU114; U5 snRNP-specific protein; 116 kDa; U5-116 kDa; EFTUD2; KIAA0031; SNRP116 |
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| Gene, Accession # | EGLN1, SwissProt: Q9GZT9 |
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| Catalog # | abx030444 |
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| Price | |
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| Order / More Info | EGLN1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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