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Antigenic Specificity | Amyloid Precursor Protein |
Clone | mAbP2-1 |
Host Species | Mouse |
Reactive Species | human, nonhuman primate |
Isotype | IgG1 |
Format | purified |
Size | 50 µg |
Concentration | n/a |
Applications | ELISA: 10 µg/mL, Immunocytochemistry: 0.5-5 µg/mL, Immunoprecipitation: 25 µg/mL*, Western Blot: 5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Amyloid Precursor Protein Monoclonal Antibody (mAbP2-1). Amyloid Precursor Protein (APP) or Amyloid beta protein functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1; APP is rapidly internalized via clathrin-coated pits. APP is important for neurite growth, neuronal adhesion and axonogenesis. Mutations in the APP gene can lead to Alzheimer disease 1 (AD1). This anitbody recognizes APP (b-APP770) with a MW of approximately 100kDa. |
Immunogen | n/a |
Other Names | APP, AAA antibody, Amyloid beta A4 protein, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP, Protease nexin-II, PN-II |
Gene, Accession # | Entrez: 351; Uniprot: P05067 |
Catalog # | OMA1-03132 |
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Order / More Info | Amyloid Precursor Protein Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 12849748, 19559702, 22984865, 25695670, 25781223, 27727204, 27997172, 28287086, 28835279 |
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