| 产品详情 |
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| Product Name | CGP 52432 |
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| Description | A GABAB receptors antagonist; selectively reverses (-)-baclofen-induced inhibition of potassium-evoked GABA release over glutamate or somatostatin release (IC50s = 0.085, 3.35, and 9.26 µM, respectively) from rat cortical synaptosomes; reduces paired-pulse inhibition of IPSPs by 80% in CA1 pyramidal neurons in rat hippocampal slices at 10 µM; increases cell proliferation in the ventral subgranular zone of the dentate gyrus when administered at a dose of 3 mg/kg per day for 21 days and reduces immobility in the forced-swim test when administered at 10 mg/kg in stress-sensitive BALB/c mice; inhibits the analgesic effects of isovaline, GABA, and baclofen in a mouse model of hindpaw allodynia induced by PGE2 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 139667-74-6 |
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| Catalog # | 27212-50 |
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| Order / More Info | CGP 52432 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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