| 产品详情 |
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| Antigenic Specificity | C-CBL |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC, IF/ICC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. |
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| Immunogen | Purified recombinant fragment of human C-CBL expressed in E. Coli. |
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| Other Names | CBL2; RNF55; E3 ubiquitin-protein ligase CBL; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; RING finger protein 55; Signal transduction protein CBL |
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| Gene, Accession # | Gene ID: 867, SwissProt: P22681 |
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| Catalog # | abx011635 |
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| Price | |
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| Order / More Info | C-CBL Antibody from ABBEXA |
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| Product Specific References | n/a |
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