| 产品详情 |
| Edit |   |
| Antigenic Specificity | CCNA1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 50 µl, 100 µl, 200 µl |
| Concentration | > 1 mg/ml |
| Applications | WB. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CCNA1 Antibody is a Rabbit Polyclonal antibody against CCNA1. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | Recombinant protein of human CCNA1. |
| Other Names | CCNA1; Cyclin-A1 |
| Gene, Accession # | CCNA1, Gene ID: 8900, SwissProt: P78396 |
| Catalog # | abx004306 |
| Price | |
| Order / More Info | CCNA1 Antibody from ABBEXA |
| Product Specific References | n/a |
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