| 产品详情 |
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| Product Name | TPX-0005 |
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| Description | TPX-0005 is a potent ALK inhibitor. It inhibits WT ALK (IC50 1.01 nM) and mutant ALKs including ALK G1202R (IC50 = 1.26 nM) and ALK L1196M (IC50 = 1.08 nM). Moreover, TPX-0005 effectively inhibits tumor growth in vivo in ALK WT and ALK G1202R xenografts. TPX-0005 is also a potent SRC inhibitor (IC50 = 5.3 nM). MW: 355.37. Purity ≥98% by HPLC |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (13E,14E,3R,6S)-45-fluoro-3,6-dimethyl-5-oxa-2,8-diaza-1(5,3)-pyrazolo[1,5-a]pyrimidina-4(1,2)-benzenacyclononaphan-9-one |
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| Gene, Accession, CAS # | CAS: 2058227-19-1 |
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| Catalog # | B2027-25 |
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| Price | |
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| Order / More Info | TPX-0005 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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